Synopsis

Source of validity: Traditional
Rating (out of 5): 2

Casticin is a flavonoid compound found in the fruit of Vitex agnus-castus (chasteberry), a plant traditionally used in herbal medicine to support the female reproductive system. The use of chasteberry, and by extension casticin, is primarily rooted in historical and traditional practices, particularly for managing symptoms of premenstrual syndrome (PMS), cyclical breast discomfort, and irregular menstrual cycles. Traditional European herbal medicine has employed extracts of the plant for centuries, based on anecdotal reports of efficacy.

Scientific research has identified casticin as one of the active constituents of Vitex agnus-castus, but most clinical studies have investigated the whole extract rather than isolated casticin. Some in vitro and animal studies suggest casticin may have dopaminergic activity, which could influence prolactin secretion, a potential mechanism for its effects on menstrual health. However, direct clinical evidence specifically linking casticin, as opposed to the whole extract, to beneficial effects on the female reproductive system is limited.

In summary, the primary justification for using casticin to support the female reproductive system is traditional, with modest scientific support for the whole plant extract and only preliminary mechanistic insights for casticin itself. The evidence rating reflects the traditional basis with limited direct scientific validation for casticin as a standalone agent.

More about casticin
More about Female Reproductive System

Other ingredients that support Female Reproductive System

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7-hydroxymatairesinol (HMR)
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AHCC
Alchemilla
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amino acids
anamu
anemarrhena asphodeloides
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animal protein
anise
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ashwagandha
barbasco
basil
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bethroot
betony
bird\'s nest
black cohosh
blessed thistle
blue cohosh
borage oil
broccoli
bugbane
Caesalpinia crista
Calochortus
casticin
Ceylon leadwort
chaste tree
Chinese pond turtle
Chlorophytum
Clary sage
Cnidium
cohosh
cramp bark
Crinum latifolium
Cynomorium
d-alpha tocopherol
daidzein
damiana
dandelion
date
DHEA
DHEA (dehydroepiandrosterone)
DIM (diindolylmethane)
dioscorea
diosgenin
dodder
dong quai
dong quai root
egg
eleuthero
equol (proprietary)
Erythrina
estrogen
evening primrose oil
evening primrose oil
false unicorn root
fatty acids
fennel
fenugreek
flaxseed
fo-ti
folate
folic acid
formononetin
furostanols
gamma linolenic acid (GLA)
genistein
giant trillium
ginger
Ginsenosides
goat\'s rue
golden ragwort
goldenseal
guelder rose
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hibiscus
HMR lignan
horny goat weed
Hypericum
Indian fagonia
Indian tinospora
indole-3-carbinol
inositol
inositol phosphate
isoflavones
jasmine
jujube
Kigelia africana
Labisia pumila
labrador tea
Lactobacillus acidophilus
Lactobacillus crispatus
Lactobacillus fermentum
Lactobacillus gasseri
Lactobacillus jensenii
Lactobacillus reuteri
Lactobacillus rhamnosus
Lactobacillus salivarius
Lady's Mantle
Laminaria
Leptadenia
lignans
ligustilides
lingzhi
linoleic acid (LA)
lipids
Loranthus
maca
macaenes
macamides
mandrake
Marine lipid
Miroestrol
Montanoa tomentosa
Motherwort
Mugwort
Nettle
Nigella seed
omega-3 fatty acids
Pennyroyal
peony
Phytoestrogens
polyunsaturated fat
Puerain
Pulsatilla
raspberry
red clover
rose
rose oil
royal jelly
Rubia cordifolia
Rubus
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Safed musli
saffron
selenium
Shataverins
shepherd's purse
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soy isoflavones
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soybean
Sparganium
spearmint leaf
squawvine
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tribulus
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vitamin B6
vitamin E
Vitex Agnus-Castus
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Other body systems supported by casticin

Estrogen
Female Reproductive System
Ovaries
Reproductive System
Uterus

Products containing casticin

We currently have no products on Vitabase that contain this ingredient.