Synopsis

Source of validity: Scientific
Rating (out of 5): 4

Inositol, particularly myo-inositol, has scientific validation for supporting the female reproductive system, especially in the context of polycystic ovary syndrome (PCOS). Multiple randomized controlled trials and meta-analyses have demonstrated that myo-inositol supplementation can improve ovarian function, restore ovulation, and enhance insulin sensitivity in women with PCOS. These effects are believed to be due to inositol's role as a secondary messenger in insulin signaling pathways, helping to reduce insulin resistance—a key factor in PCOS-related reproductive dysfunction. Additionally, inositol has been shown to improve hormonal profiles (including reducing elevated testosterone) and menstrual cyclicity. Some studies also suggest benefits for oocyte quality in women undergoing assisted reproductive technologies.

The level of evidence is strongest for inositol’s use in women with PCOS, where guidelines from organizations such as the International Evidence-Based Guideline for the Assessment and Management of PCOS (2018) recommend considering inositol as a supplement for metabolic and reproductive aspects of the syndrome. However, evidence is more limited or inconclusive for other reproductive conditions or for use in women without PCOS. Overall, inositol is not only traditionally used but is supported by a robust and growing body of scientific research for specific female reproductive health concerns.

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Other ingredients that support Female Reproductive System

Other body systems supported by inositol

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