Evidence supporting the use of: Ligustilides
For the body system: Female Reproductive System

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Synopsis

Source of validity: Traditional
Rating (out of 5): 2

Ligustilides are a class of phthalide compounds most notably found in the roots of Angelica sinensis (Dong Quai) and Ligusticum chuanxiong, both staples of traditional Chinese medicine (TCM). Historically, these herbs have been used for centuries in Asia to support female reproductive health, particularly for regulating menstrual cycles, alleviating menstrual cramps, and addressing symptoms of menopause. The rationale for their use in TCM is based on their purported ability to "invigorate blood" and "dispel wind," concepts rooted in TCM theory rather than Western biomedical science.

Some preliminary pharmacological studies indicate that ligustilide may have antispasmodic, anti-inflammatory, and vasodilatory effects, which could theoretically support uterine health and alleviate dysmenorrhea, but most of this research is limited to in vitro or animal models. There is a lack of robust clinical trials in humans that definitively validate these effects or establish safety and efficacy for supporting the female reproductive system. Thus, the use of ligustilides for this purpose is primarily justified by a long history of traditional use rather than strong scientific validation.

More about ligustilides
More about Female Reproductive System

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Products containing ligustilides

We currently have no products on Vitabase that contain this ingredient.