Evidence supporting the use of: Macamides
For the body system: Female Reproductive System
Synopsis
Source of validity: Traditional
Rating (out of 5): 2
Macamides are bioactive compounds unique to the maca plant (Lepidium meyenii), which has a long history of traditional use in the Andes for enhancing fertility and supporting the female reproductive system. The use of maca root by indigenous peoples, particularly women, dates back centuries and is rooted in its reputation for balancing hormones, improving menstrual health, and enhancing libido. While animal studies and a handful of small human studies have indicated that maca may influence reproductive hormones and improve symptoms associated with menopause, the specific role of macamides is less well-defined in the scientific literature. Most available research focuses on the whole maca root or extracts, not isolated macamides. Thus, while there is a strong tradition supporting its use for female reproductive health, scientific validation is limited and more robust clinical evidence is needed to confirm efficacy and clarify mechanisms. Currently, the evidence supporting macamides specifically for female reproductive health is based primarily on traditional use, with a moderate (2/5) evidence rating due to the lack of direct, high-quality clinical studies.
Other ingredients that support Female Reproductive System
7-hydroxymatairesinol (HMR)amino acids
ashwagandha
basil
black cohosh
borage oil
broccoli
chaste tree
turmeric
d-alpha tocopherol
damiana
dandelion
DHEA (dehydroepiandrosterone)
DIM (diindolylmethane)
dong quai root
eleuthero
evening primrose oil
fennel
fenugreek
flaxseed
folate
gamma linolenic acid (GLA)
genistein
ginger
goldenseal
hibiscus
HMR lignan
Indian tinospora
indole-3-carbinol
inositol
jujube
lactobacillus acidophilus
lactobacillus crispatus
lactobacillus fermentum
lactobacillus gasseri
lactobacillus jensenii
lactobacillus reuteri
lactobacillus rhamnosus
lactobacillus salivarius
lignans
linoleic acid (LA)
maca
marine lipid
motherwort
nettle
omega-3 fatty acids
raspberry
rose oil
saffron
selenium
soybean
spearmint leaf
tribulus
vitamin B
vitamin B6
vitamin E
wild yam
red clover
squawvine
mugwort
anise
caesalpinia crista
rubia cordifolia
blessed thistle
peony
lingzhi
lingusticum wallichii
yarrow
yarrow
dioscorea
dodder
royal jelly
Equol (proprietary)
guelder rose
trace minerals
anemarrhena asphodeloides
shepherd's purse
wood betony
herbal blend (proprietary)
soy isoflavones
27-deoxyactein
25-d-spirosta-3, 5-diene
8-Prenylnaringenin
Angelica
Anamu
AHCC
Alchemilla
Aletris
Anserina
Anemone
Agnuside
Ashoka
Abuta
Animal protein
Betony
Blue Cohosh
Bugbane
Bethroot
Barbasco
Belamcanda
Bird's nest
Calochortus
Cohosh
Clary sage
Cnidium
Cynomorium
Cramp Bark
Chinese Pond Turtle
Chlorophytum
Casticin
Ceylon Leadwort
Crinum latifolium
DHEA
Daidzein
Dong Quai
Diosgenin
Date
Egg
Erythrina
Evening Primrose Oil
Estrogen
Folic Acid
False Unicorn Root
Isoflavones
jasmine
Pennyroyal
Rose
Soy Protein
Vervain
Other body systems supported by Macamides
Adrenal GlandsBrain
Dopamine
Female Reproductive System
Glandular System
Male Reproductive System
Reproductive System
Specific Hormones
Testosterone