Evidence supporting the use of: Vitamin B9 (calcium methylfolate)
For the body system: Female Reproductive System

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Synopsis

Source of validity: Scientific
Rating (out of 5): 5

Vitamin B9, particularly in the form of calcium methylfolate (a bioavailable form of folate), is scientifically validated for supporting the female reproductive system, especially in the context of preconception and pregnancy. Folate is essential for DNA synthesis, cell division, and the proper closure of the neural tube during embryonic development. Deficiency of folate in women of childbearing age is strongly associated with an increased risk of neural tube defects (NTDs) such as spina bifida and anencephaly in offspring. Numerous clinical trials and epidemiological studies have shown that adequate intake of folate before conception and during early pregnancy significantly reduces the incidence of NTDs. For this reason, health authorities such as the Centers for Disease Control and Prevention (CDC), World Health Organization (WHO), and American College of Obstetricians and Gynecologists (ACOG) recommend that women who are planning pregnancy or who may become pregnant take supplemental folate. Calcium methylfolate is often preferred over folic acid in certain populations due to its enhanced bioavailability and effectiveness, particularly in individuals with MTHFR gene polymorphisms that impair folic acid metabolism. Overall, the use of Vitamin B9 (calcium methylfolate) is well-supported by robust scientific evidence for supporting the female reproductive system, particularly for fetal neural development and maternal health during pregnancy.

More about Vitamin B9 (calcium methylfolate)
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7-hydroxymatairesinol (HMR)
amino acids
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basil
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borage oil
broccoli
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DHEA (dehydroepiandrosterone)
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dong quai root
eleuthero
evening primrose oil
fennel
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flaxseed
folate
gamma linolenic acid (GLA)
genistein
ginger
goldenseal
hibiscus
HMR lignan
Indian tinospora
indole-3-carbinol
inositol
jujube
lactobacillus acidophilus
lactobacillus crispatus
lactobacillus fermentum
lactobacillus gasseri
lactobacillus jensenii
lactobacillus reuteri
lactobacillus rhamnosus
lactobacillus salivarius
lignans
linoleic acid (LA)
maca
marine lipid
motherwort
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omega-3 fatty acids
raspberry
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saffron
selenium
soybean
spearmint leaf
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vitamin B6
vitamin E
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rubia cordifolia
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peony
lingzhi
lingusticum wallichii
yarrow
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dioscorea
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trace minerals
anemarrhena asphodeloides
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wood betony
herbal blend (proprietary)
soy isoflavones
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AHCC
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Betony
Blue Cohosh
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Cnidium
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Products containing Vitamin B9 (calcium methylfolate)

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