Evidence supporting the use of: Coenzyme Q10 (CoQ10)
For the health condition: Free Radical Damage
Synopsis
Source of validity: Scientific
Rating (out of 5): 3
Coenzyme Q10 (CoQ10) is justified by scientific validation for use in supporting or treating free radical damage. CoQ10 is a lipid-soluble antioxidant naturally present in the mitochondria of cells, where it plays a crucial role in the electron transport chain and energy production. Its antioxidant properties allow it to neutralize free radicals and reduce oxidative stress, which is a key contributor to cellular damage and aging. Several in vitro and animal studies have demonstrated that CoQ10 supplementation can decrease markers of oxidative damage in tissues. In humans, clinical studies have shown that CoQ10 supplementation can increase antioxidant capacity in plasma and reduce biomarkers of oxidative stress, particularly in populations with increased oxidative burden, such as individuals with cardiovascular disease, diabetes, and neurodegenerative disorders.
However, while the biochemical basis and preclinical data are robust, clinical trials in healthy populations or for general prevention of oxidative damage are less conclusive, and the translation to broad therapeutic recommendations is still debated. The evidence is strongest for specific conditions associated with increased oxidative stress, but more research is needed to fully establish its efficacy for general free radical damage in otherwise healthy individuals. Overall, current data support a moderate scientific basis (rated 3 out of 5) for the use of CoQ10 in managing free radical damage, particularly in clinical contexts with elevated oxidative stress.
More about coenzyme Q10 (CoQ10)
More about Free Radical Damage
Other ingredients used for Free Radical Damage
7-hydroxymatairesinol (HMR)acai berry
acetyl l-carnitine
alpha-carotene
alpha-glycosyl isoquercitrin
amino acids
anthocyanins
apricot
ascorbyl palmitate
astaxanthin
astragalus
basil
berry flavor
beta-carotene
beta-tocopherol
bilberry
black currant
black garlic
black tea
blackberry
blueberry
broccoli
brussel sprouts
caffeine
camu camu
catalase
catechins
caterpillar mushroom
cauliflower
chokeberry
chrysin
coconut milk
coenzyme Q10 (CoQ10)
coffee fruit
cryptoxanthin
turmeric
delta-tocopherol
epigallocatechin gallate (EGCG)
fish protein
flavonols
fruit blend (proprietary)
ginseng
grape
green tea
greens blend (proprietary)
guarana
hesperetin
hesperidin
HMR lignan
l-carnosine
l-cysteine
l-glutathione
l-glycine
lentinula edodes mycelia
lutein
matcha
melatonin
mixed carotenoids
n-acetyl-cysteine (NAC)
nicotinamide riboside
omega-3 fatty acids
oyster mushroom
phenolic acids
phospholipids
pine bark
pyrroloquinoline disodium salt
quercetin
raspberry
reishi mushroom
resveratrol
selenium
spirulina
strawberry
ubiquinol
vegetable blend (proprietary)
vitamin C
vitamin E
whey protein
zinc
papaya
bee pollen
lingzhi
ferulic acid
cistanche
ganoderma
royal jelly
polyphenols
fulvic acid
wheat germ
goji berry
algae
cocoa
1,2-di-galloyl-4,6hexahydroxydiphenoyl-D-glucose
3,3'-dihydroxy-B-carotene-4,4'-dione
3-Isomangostin
5,7-Dimethoxyflavone
7,4-Dimethoxyflavone
Amethoflavone
Ankaflavin
Apigenin
Aronia melanocarpa
Auricularia
Autumn Olive
Antirrhinin
Avocado
Amentoflavone
Acacetin
Allophycocyanin
Alpha-Lipoic Acid
Ascorbigen
Astragaloside
anthocyanidins
Algal protein
Acer Truncatum bunge
anthocyanosides
Argan nut oil
Apocarotenal
Apocynin
Arctiin
Arjunolic acid
Beta-hydroxybutyrate
beta-zeacarotene
Brassica
Bok Choy
Baccosides
BHT (Butylated Hydroxytoluene)
Benfotiamine
Basidiomycota
Betanin
berry
Brazil nut
boysenberry
BHA (butylated hydroxyanisole)
Bioflavonoids
bacoside
Baicalin
Caffeic Acid
Camellia sinensis
Carnosine
Chebulic acid
Cashew
Cichoric acid
Chocolate
Capsorubin
Carnosol
Cupric ascorbate
C-Phycocyanin
Carotene (unspecified)
Chebulinic acid
Crocetin
Canthaxanthin
Crypthecodinium
Capsanthin
Carnosic acid
Dunaliella salina
Dismutase
Delphinidin
Dunaliella
Dehydroascorbic acid
Dumontiaceae
Desoxyrhaponticin
Dragon Fruit
Dibenzo-alpha pyrones
Dihydrolipoic Acid
Diosmetin
epicatechin
Ellagic Acid
Ergothioneine
Emblicanin
Erythorbic acid
Ethylgallate
Eriodictyol
Ecklonia
Flavonones
walnut
Other health conditions supported by coenzyme Q10 (CoQ10)
Aging (prevention)Alzheimer's Disease
Angina
Apathy
Arrhythmia
Arteriosclerosis
Athletic and Exercise Aids
Cancer Treatment (reducing side effects)
Cardiac Arrest
Cardiovascular Disease
Chemotherapy (reducing side effects)
Circulation (poor)
Congestive Heart Failure
Depression
Diabetes
Endurance (lack of)
Energy (lack of)
Exercise
Fatigue
Fibromyalgia Syndrome
Free Radical Damage
Heart (weakness)
Heart Fibrillation or Palpitations
Hypertension
Memory and Brain Function
Migraine
Multiple Sclerosis
Muscle Tone (lack of)
Muscular Dystrophy
Nerve Damage
Oral Surgery
Parkinson's Disease
Peripheral Neuropathy
Rheumatoid Arthritis
Tinnitus
Products containing coenzyme Q10 (CoQ10)
Pure Encapsulations
Athletic Nutrients
Douglas Laboratories
Citrus-Q10 ™
Douglas Laboratories
Co-Enzyme Q10 Softgel
Douglas Laboratories
Coenzyme Q-10 with Lipoic Acid
Douglas Laboratories
Coenzyme Q-10 with Lipoic Acid
Integrative Therapeutics
CoQ10
Integrative Therapeutics
COQ10 100 mg Tropical
Pure Encapsulations
CoQ10 120 mg
Pure Encapsulations
CoQ10 120 mg
Pure Encapsulations
CoQ10 120 mg
Integrative Therapeutics
COQ10 200 mg Chocolate 30 chew tabs
Pure Encapsulations
CoQ10 250 mg
Pure Encapsulations
CoQ10 30 mg
Pure Encapsulations
CoQ10 500 mg
Pure Encapsulations
CoQ10 60 mg
Pure Encapsulations
CoQ10 60 mg
Pure Encapsulations
CoQ10 60 mg
Pure Encapsulations
CoQ10 l-Carnitine Fumarate
Thorne
CoQ10 Q-Best 100
Metagenics
CoQ10 ST®-100 mg
Metagenics
CoQ10 ST-100 mg
Metagenics
CoQ10 ST-200 mg
Integrative Therapeutics
Detoxication Factors
Integrative Therapeutics
Detoxication Factors
Pure Encapsulations
Energize Plus™ Pure Pack
Pure Encapsulations
Hair/Skin/Nails Ultra
Thorne
Heart Health Complex Q-10 Plus
Integrative Therapeutics
K-PAX MitoNutrients
Vitabase
Life's Essentials Plus
Designs For Health
Mito-NR™
Pure Encapsulations
Mitochondria-ATP
Designs For Health
Mitochondrial NRG™
Pure Encapsulations
NeuroMood Pure Pack
Metagenics
NutraGems® CoQ10 300
Pure Encapsulations
O.N.E.™ Multivitamin
Pure Encapsulations
O.N.E.™ Multivitamin
Pure Encapsulations
O.N.E.™ Multivitamin
Thorne
Omega-3 w/ CoQ10
Thorne
Ovarian Care
Integrative Therapeutics
ProThrivers Wellness Flav Complex
Pure Encapsulations
PureGenomics® UltraMultivitamin
Designs For Health
Q-Evail® 100
Designs For Health
Q-Evail® 200
Pure Encapsulations
Q-Gel® (Hydrosoluble™ CoQ10) 100 mg
Thorne
Red Yeast Rice + CoQ10 Choleast
Pure Encapsulations
Renual
Pure Encapsulations
RevitalAge™ Nerve
Pure Encapsulations
RevitalAge™ Ultra
Designs For Health
RYR Synergy™
Pure Encapsulations
SR-CoQ10 with PQQ
Vitabase
Super Fat Burner
Pure Encapsulations
Ubiquinol-QH 100 mg
Pure Encapsulations
Ubiquinol-QH 200 mg
Pure Encapsulations
Ubiquinol VESIsorb®
Integrative Therapeutics
UBQH 100 mg
Douglas Laboratories
Ultra Preventive 50+ -EZ Swallow
Douglas Laboratories
Ultra Preventive One Daily
Pure Encapsulations
Ultra Pure Pack
Pure Encapsulations
UltraDetox 10-Day Pure Pack
Pure Encapsulations
UltraNutrient®
Pure Encapsulations
UltraNutrient®
Pure Encapsulations
UltraNutrient®
Metagenics
Wellness Essentials Brain Health Daily Packs