Evidence supporting the use of: Fatty acids
For the health condition: Free Radical Damage

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Synopsis

Source of validity: Scientific
Rating (out of 5): 3

Fatty acids, particularly omega-3 and omega-6 polyunsaturated fatty acids, have scientific evidence supporting their role in countering free radical damage, mainly through their influence on inflammation and antioxidant systems. Free radicals cause oxidative stress, which can damage cellular components such as lipids, proteins, and DNA. Omega-3 fatty acids (such as EPA and DHA) have been shown in several in vitro and in vivo studies to modulate the body's antioxidant defenses by upregulating enzymes like superoxide dismutase, catalase, and glutathione peroxidase. These mechanisms help neutralize free radicals. Additionally, some clinical studies suggest that omega-3 supplementation can reduce biomarkers of oxidative stress in humans, though results can be inconsistent and are often dependent on baseline antioxidant status and health condition.

However, it is important to note that fatty acids themselves can also be susceptible to peroxidation (i.e., being damaged by free radicals), especially in the case of polyunsaturated fats. This dual role means that while fatty acids may bolster antioxidant defenses and reduce inflammation, excessive or unbalanced intake might promote oxidative stress under certain conditions. Overall, while there is moderate scientific support (evidence level 3 out of 5) for the use of fatty acids in supporting the body against free radical damage, more large-scale, controlled human trials are needed to establish optimal dosages and clarify the extent of benefit.

More about fatty acids
More about Free Radical Damage

Other ingredients used for Free Radical Damage

1,2-di-galloyl-4,6hexahydroxydiphenoyl-D-glucose
3,3'-dihydroxy-B-carotene-4,4'-dione
3-Isomangostin
5,7-Dimethoxyflavone
7,4-Dimethoxyflavone
7-hydroxymatairesinol (HMR)
Acacetin
Acai berry
Acer truncatum
Acetyl L-carnitine
Algae
Algal protein
Allophycocyanin
Alpha-carotene
alpha-glycosyl isoquercitrin
alpha-lipoic acid
amentoflavone
amethoflavone
amino acids
ankaflavin
anthocyanidins
anthocyanins
anthocyanosides
antirrhinin
apigenin
apocarotenal
apocynin
apricot
arctiin
argan nut oil
Arjunolic acid
Aronia melanocarpa
ascorbigen
ascorbyl palmitate
astaxanthin
astragaloside
astragalus
Auricularia
Autumn Olive
avocado
baccosides
bacoside
baicalin
Basidiomycota
basil
bee pollen
benfotiamine
berry
beta-carotene
beta-hydroxybutyrate
beta-tocopherol
beta-zeacarotene
betanin
BHA (butylated hydroxyanisole)
BHT (butylated hydroxytoluene)
bilberry
bioflavonoids
black currant
black garlic
black tea
blackberry
blueberry
bok choy
boysenberry
Brassica
Brazil nut
broccoli
Brussel sprouts
C-phycocyanin
caffeic Acid
caffeine
Camellia sinensis
camu camu
canthaxanthin
capsanthin
capsorubin
carnosic acid
Carnosine
carnosol
carotene (unspecified)
cashew
catalase
catechins
caterpillar mushroom
cauliflower
chebulic acid
chebulinic acid
chocolate
chokeberry
chrysin
cichoric acid
cistanche
cocoa
coconut milk
coenzyme Q10 (CoQ10)
coffee fruit
crocetin
Crypthecodinium
cryptoxanthin
cupric ascorbate
dehydroascorbic acid
delphinidin
delta-tocopherol
desoxyrhaponticin
dibenzo-alpha pyrones
dihydrolipoic acid
diosmetin
dismutase
dragon fruit
Dumontiaceae
Dunaliella
Dunaliella salina
Ecklonia
ellagic acid
emblicanin
epicatechin
epigallocatechin gallate (EGCG)
ergothioneine
eriodictyol
erythorbic acid
ethylgallate
fatty acids
ferulic acid
fish protein
flavanones
flavans
flavin mononucleotide
flavoglycosides
flavones
flavonols
flavonones
fruit blend (proprietary)
fucoidan
fulvic acid
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Gac
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gamma-glutamylcysteine
ganoderma
Garcinone C
Garcinone E
ginseng
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Glutathione
goji berry
grape
green tea
greens blend (proprietary)
guarana
Haematococcus pluvialis
hesperetin
hesperidin
HMR lignan
honeybush
hydroxycinnamic acid
hydroxyphenylethanols
hydroxytyrosol
Idebenone
isoascorbate
isovitexin
Jaboticaba
Kaempferol
kucha tea
L-carnosine
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Lentinula edodes mycelia
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lingzhi
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Matcha
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mixed carotenoids
Myricitrin
N-acetyl-cysteine (NAC)
N-Caffeoyldopamine
Neoandrographolides
Neoxanthin
nicotinamide riboside
Oligomeric proanthocyanidins
omega-3 fatty acids
oyster mushroom
papaya
Pecan
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phenolic compounds
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phospholipids
Phthalides
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pine bark
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procyanidin
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propyl gallate
punicalagins
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Pycnogenol
pyrroloquinoline disodium salt
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quercetin
raspberry
reishi mushroom
resveratrol
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royal jelly
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selenium
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spirulina
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strawberry
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Trigalloyl glucose
turmeric
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ubiquinol
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Vanillin
vegetable blend (proprietary)
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vitamin C
vitamin E
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Xylaria nigripes
Yumberry
Zinc

Products containing fatty acids

We currently have no products on Vitabase that contain this ingredient.