Evidence supporting the use of: Ginsenosides (unspecified)
For the health condition: Free Radical Damage
Synopsis
Source of validity: Scientific
Rating (out of 5): 3
Ginsenosides, the primary active compounds found in ginseng species such as Panax ginseng and Panax quinquefolius, are recognized for their antioxidant properties. Several in vitro and animal studies have demonstrated that various ginsenosides (such as Rb1, Rg1, and Re) can scavenge free radicals, upregulate endogenous antioxidant enzymes (including superoxide dismutase, catalase, and glutathione peroxidase), and reduce oxidative stress markers. These effects suggest a mechanistic basis for the potential use of ginsenosides in supporting the body’s defense against free radical damage.
However, while preclinical research is robust, human clinical trial data are limited and often involve small sample sizes or surrogate endpoints. A few clinical studies have indicated that ginseng supplementation might reduce biomarkers of oxidative stress in healthy volunteers or certain patient populations, but results are mixed and not universally conclusive. Therefore, the scientific evidence supporting ginsenosides for free radical damage is promising but not definitive, warranting a moderate evidence rating (3/5).
In summary, the antioxidant effects of ginsenosides are supported by substantial laboratory and animal research, with some preliminary human data. More rigorous, large-scale clinical trials are needed to confirm their efficacy in mitigating free radical damage in humans.
More about Ginsenosides (unspecified)
More about Free Radical Damage
Other ingredients used for Free Radical Damage
7-hydroxymatairesinol (HMR)acai berry
acetyl l-carnitine
alpha-carotene
alpha-glycosyl isoquercitrin
amino acids
anthocyanins
apricot
ascorbyl palmitate
astaxanthin
astragalus
basil
berry flavor
beta-carotene
beta-tocopherol
bilberry
black currant
black garlic
black tea
blackberry
blueberry
broccoli
brussel sprouts
caffeine
camu camu
catalase
catechins
caterpillar mushroom
cauliflower
chokeberry
chrysin
coconut milk
coenzyme Q10 (CoQ10)
coffee fruit
cryptoxanthin
turmeric
delta-tocopherol
epigallocatechin gallate (EGCG)
fish protein
flavonols
fruit blend (proprietary)
ginseng
grape
green tea
greens blend (proprietary)
guarana
hesperetin
hesperidin
HMR lignan
l-carnosine
l-cysteine
l-glutathione
l-glycine
lentinula edodes mycelia
lutein
matcha
melatonin
mixed carotenoids
n-acetyl-cysteine (NAC)
nicotinamide riboside
omega-3 fatty acids
oyster mushroom
phenolic acids
phospholipids
pine bark
pyrroloquinoline disodium salt
quercetin
raspberry
reishi mushroom
resveratrol
selenium
spirulina
strawberry
ubiquinol
vegetable blend (proprietary)
vitamin C
vitamin E
whey protein
zinc
papaya
bee pollen
lingzhi
ferulic acid
cistanche
ganoderma
royal jelly
polyphenols
fulvic acid
wheat germ
goji berry
algae
cocoa
1,2-di-galloyl-4,6hexahydroxydiphenoyl-D-glucose
3,3'-dihydroxy-B-carotene-4,4'-dione
3-Isomangostin
5,7-Dimethoxyflavone
7,4-Dimethoxyflavone
Amethoflavone
Ankaflavin
Apigenin
Aronia melanocarpa
Auricularia
Autumn Olive
Antirrhinin
Avocado
Amentoflavone
Acacetin
Allophycocyanin
Alpha-Lipoic Acid
Ascorbigen
Astragaloside
anthocyanidins
Algal protein
Acer Truncatum bunge
anthocyanosides
Argan nut oil
Apocarotenal
Apocynin
Arctiin
Arjunolic acid
Beta-hydroxybutyrate
beta-zeacarotene
Brassica
Bok Choy
Baccosides
BHT (Butylated Hydroxytoluene)
Benfotiamine
Basidiomycota
Betanin
berry
Brazil nut
boysenberry
BHA (butylated hydroxyanisole)
Bioflavonoids
bacoside
Baicalin
Caffeic Acid
Camellia sinensis
Carnosine
Chebulic acid
Cashew
Cichoric acid
Chocolate
Capsorubin
Carnosol
Cupric ascorbate
C-Phycocyanin
Carotene (unspecified)
Chebulinic acid
Crocetin
Canthaxanthin
Crypthecodinium
Capsanthin
Carnosic acid
Dunaliella salina
Dismutase
Delphinidin
Dunaliella
Dehydroascorbic acid
Dumontiaceae
Desoxyrhaponticin
Dragon Fruit
Dibenzo-alpha pyrones
Dihydrolipoic Acid
Diosmetin
epicatechin
Ellagic Acid
Ergothioneine
Emblicanin
Erythorbic acid
Ethylgallate
Eriodictyol
Ecklonia
Flavonones
walnut
Other health conditions supported by Ginsenosides (unspecified)
Alzheimer's DiseaseAnxiety
Arthritis
Asthma
Cancer (natural therapy for)
Cancer (prevention)
Cancer Treatment (reducing side effects)
Cardiovascular Disease
Cholesterol (high)
Circulation (poor)
Concentration (poor)
Depression
Diabetes
Digestion (poor)
Fatigue
Free Radical Damage
Gastritis
Hypertension
Inflammation
Memory and Brain Function
Menopause
Muscle Tone (lack of)
Nervous Exhaustion
Osteoporosis
Parkinson's Disease
Sex Drive (low)
Stress
Triglycerides (high)
Wounds and Sores