Evidence supporting the use of: Proprietary Blend (Fatty Acid or Fat/Oil supplement)
For the health condition: Free Radical Damage
Synopsis
Source of validity: Scientific
Rating (out of 5): 2
Fatty acid or fat/oil supplements, such as fish oil (rich in omega-3 fatty acids EPA and DHA), have been studied for their potential to counteract free radical damage, which is associated with oxidative stress and chronic inflammation. Scientific evidence indicates that certain fatty acids possess antioxidant properties, either directly or by modulating antioxidant defense systems in the body. Some studies have shown that omega-3 supplementation can increase the activity of endogenous antioxidant enzymes (e.g., superoxide dismutase, catalase) and reduce markers of oxidative stress in various populations, including those with chronic diseases. However, the evidence is mixed, with some clinical trials reporting limited or no effect on direct markers of free radical damage. The purported mechanism involves both the reduction of inflammatory mediators and the improvement of cell membrane integrity, which may indirectly reduce oxidative stress. It is important to note that while there is a plausible biological mechanism, and some supportive data from laboratory and clinical studies, the overall quality and consistency of evidence are moderate and not definitive. Some proprietary blends may also include other oils or additives with unclear roles in combating free radical damage. Therefore, while the use of fatty acid supplements for this purpose is grounded in scientific rationale and some evidence, it is not strongly validated, and further well-designed clinical trials are needed to clarify their efficacy for this indication.
More about Proprietary Blend (Fatty Acid or Fat/Oil supplement)
More about Free Radical Damage
Other ingredients used for Free Radical Damage
7-hydroxymatairesinol (HMR)acai berry
acetyl l-carnitine
alpha-carotene
alpha-glycosyl isoquercitrin
amino acids
anthocyanins
apricot
ascorbyl palmitate
astaxanthin
astragalus
basil
berry flavor
beta-carotene
beta-tocopherol
bilberry
black currant
black garlic
black tea
blackberry
blueberry
broccoli
brussel sprouts
caffeine
camu camu
catalase
catechins
caterpillar mushroom
cauliflower
chokeberry
chrysin
coconut milk
coenzyme Q10 (CoQ10)
coffee fruit
cryptoxanthin
turmeric
delta-tocopherol
epigallocatechin gallate (EGCG)
fish protein
flavonols
fruit blend (proprietary)
ginseng
grape
green tea
greens blend (proprietary)
guarana
hesperetin
hesperidin
HMR lignan
l-carnosine
l-cysteine
l-glutathione
l-glycine
lentinula edodes mycelia
lutein
matcha
melatonin
mixed carotenoids
n-acetyl-cysteine (NAC)
nicotinamide riboside
omega-3 fatty acids
oyster mushroom
phenolic acids
phospholipids
pine bark
pyrroloquinoline disodium salt
quercetin
raspberry
reishi mushroom
resveratrol
selenium
spirulina
strawberry
ubiquinol
vegetable blend (proprietary)
vitamin C
vitamin E
whey protein
zinc
papaya
bee pollen
lingzhi
ferulic acid
cistanche
ganoderma
royal jelly
polyphenols
fulvic acid
wheat germ
goji berry
algae
cocoa
1,2-di-galloyl-4,6hexahydroxydiphenoyl-D-glucose
3,3'-dihydroxy-B-carotene-4,4'-dione
3-Isomangostin
5,7-Dimethoxyflavone
7,4-Dimethoxyflavone
Amethoflavone
Ankaflavin
Apigenin
Aronia melanocarpa
Auricularia
Autumn Olive
Antirrhinin
Avocado
Amentoflavone
Acacetin
Allophycocyanin
Alpha-Lipoic Acid
Ascorbigen
Astragaloside
anthocyanidins
Algal protein
Acer Truncatum bunge
anthocyanosides
Argan nut oil
Apocarotenal
Apocynin
Arctiin
Arjunolic acid
Beta-hydroxybutyrate
beta-zeacarotene
Brassica
Bok Choy
Baccosides
BHT (Butylated Hydroxytoluene)
Benfotiamine
Basidiomycota
Betanin
berry
Brazil nut
boysenberry
BHA (butylated hydroxyanisole)
Bioflavonoids
bacoside
Baicalin
Caffeic Acid
Camellia sinensis
Carnosine
Chebulic acid
Cashew
Cichoric acid
Chocolate
Capsorubin
Carnosol
Cupric ascorbate
C-Phycocyanin
Carotene (unspecified)
Chebulinic acid
Crocetin
Canthaxanthin
Crypthecodinium
Capsanthin
Carnosic acid
Dunaliella salina
Dismutase
Delphinidin
Dunaliella
Dehydroascorbic acid
Dumontiaceae
Desoxyrhaponticin
Dragon Fruit
Dibenzo-alpha pyrones
Dihydrolipoic Acid
Diosmetin
epicatechin
Ellagic Acid
Ergothioneine
Emblicanin
Erythorbic acid
Ethylgallate
Eriodictyol
Ecklonia
Flavonones
walnut
Other health conditions supported by Proprietary Blend (Fatty Acid or Fat/Oil supplement)
ArthritisAttention Deficit Disorder
Autoimmune Disorders
Bipolar Mood Disorder
Cardiovascular Disease
Cholesterol (high)
Convalescence
Depression
Dermatitis
Diabetes
Dysmenorrhea
Eczema
Energy (lack of)
Free Radical Damage
Heart (weakness)
Hypertension
Inflammation