Synopsis

Source of validity: Scientific
Rating (out of 5): 3

Ribose-l-cysteine is a synthetic compound designed to efficiently deliver cysteine, a key precursor for the endogenous antioxidant glutathione. Free radical damage, also known as oxidative stress, is implicated in a wide range of diseases and aging-related changes. Ribose-l-cysteine has been studied for its potential to boost glutathione levels more effectively than dietary cysteine or N-acetylcysteine (NAC), which can be limited by poor bioavailability or side effects.

Preclinical studies (in vitro and animal models) have shown that ribose-l-cysteine supplementation increases glutathione synthesis, enhances antioxidant defenses, and reduces markers of oxidative stress. For example, research published in peer-reviewed journals indicates that ribose-l-cysteine can decrease lipid peroxidation and DNA damage caused by free radicals in animal models. Additionally, some studies suggest it may offer protection in models of liver toxicity, cardiovascular stress, and diabetic complications.

However, human studies are limited. While there is a strong biochemical rationale and a growing body of preclinical data supporting its use for protecting against free radical damage, there is not yet robust clinical trial evidence in humans. Thus, ribose-l-cysteine is best described as having scientific support at the preclinical stage, with moderate evidence (level 3/5) for use against free radical damage based on current research.

More about Ribose-l-cysteine
More about Free Radical Damage

Other ingredients used for Free Radical Damage

1,2-di-galloyl-4,6hexahydroxydiphenoyl-D-glucose
3,3'-dihydroxy-B-carotene-4,4'-dione
3-Isomangostin
5,7-Dimethoxyflavone
7,4-Dimethoxyflavone
7-hydroxymatairesinol (HMR)
Acacetin
Acai berry
Acer truncatum
Acetyl L-carnitine
Algae
Algal protein
Allophycocyanin
Alpha-carotene
alpha-glycosyl isoquercitrin
alpha-lipoic acid
amentoflavone
amethoflavone
amino acids
ankaflavin
anthocyanidins
anthocyanins
anthocyanosides
antirrhinin
apigenin
apocarotenal
apocynin
apricot
arctiin
argan nut oil
Arjunolic acid
Aronia melanocarpa
ascorbigen
ascorbyl palmitate
astaxanthin
astragaloside
astragalus
Auricularia
Autumn Olive
avocado
baccosides
bacoside
baicalin
Basidiomycota
basil
bee pollen
benfotiamine
berry
beta-carotene
beta-hydroxybutyrate
beta-tocopherol
beta-zeacarotene
betanin
BHA (butylated hydroxyanisole)
BHT (butylated hydroxytoluene)
bilberry
bioflavonoids
black currant
black garlic
black tea
blackberry
blueberry
bok choy
boysenberry
Brassica
Brazil nut
broccoli
Brussel sprouts
C-phycocyanin
caffeic Acid
caffeine
Camellia sinensis
camu camu
canthaxanthin
capsanthin
capsorubin
carnosic acid
Carnosine
carnosol
carotene (unspecified)
cashew
catalase
catechins
caterpillar mushroom
cauliflower
chebulic acid
chebulinic acid
chocolate
chokeberry
chrysin
cichoric acid
cistanche
cocoa
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coenzyme Q10 (CoQ10)
coffee fruit
crocetin
Crypthecodinium
cryptoxanthin
cupric ascorbate
dehydroascorbic acid
delphinidin
delta-tocopherol
desoxyrhaponticin
dibenzo-alpha pyrones
dihydrolipoic acid
diosmetin
dismutase
dragon fruit
Dumontiaceae
Dunaliella
Dunaliella salina
Ecklonia
ellagic acid
emblicanin
epicatechin
epigallocatechin gallate (EGCG)
ergothioneine
eriodictyol
erythorbic acid
ethylgallate
fatty acids
ferulic acid
fish protein
flavanones
flavans
flavin mononucleotide
flavoglycosides
flavones
flavonols
flavonones
fruit blend (proprietary)
fucoidan
fulvic acid
furanosterols
Gac
gamma-carotene
gamma-glutamylcysteine
ganoderma
Garcinone C
Garcinone E
ginseng
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Glutathione
goji berry
grape
green tea
greens blend (proprietary)
guarana
Haematococcus pluvialis
hesperetin
hesperidin
HMR lignan
honeybush
hydroxycinnamic acid
hydroxyphenylethanols
hydroxytyrosol
Idebenone
isoascorbate
isovitexin
Jaboticaba
Kaempferol
kucha tea
L-carnosine
L-cysteine
L-glutathione
L-glycine
Lentinula edodes mycelia
Leucodelphinidin
lingzhi
lipids
lutein
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macadamia
malvidin
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mangostanol
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Matcha
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Methoxylated flavones
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Mineral ascorbate
mixed carotenoids
Myricitrin
N-acetyl-cysteine (NAC)
N-Caffeoyldopamine
Neoandrographolides
Neoxanthin
nicotinamide riboside
Oligomeric proanthocyanidins
omega-3 fatty acids
oyster mushroom
papaya
Pecan
Pentacyclic triterpenoids
Pentose phosphate
phenolic compounds
Phosphate ascorbate
phospholipids
Phthalides
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Phytoene
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Phytoplankton
pine bark
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Pleurotus eryngii
polymethoxylated flavones
polyphenols
polyporous mushroom
proanthocyanidins
procyanidin
procyanidol
propyl gallate
punicalagins
punicosides
Pycnogenol
pyrroloquinoline disodium salt
pyrroloquinoline quinone
quercetin
raspberry
reishi mushroom
resveratrol
rhammetin
Ribose-l-cysteine
robusta coffee
Rooibos
rosmarinic acid
royal jelly
Salidroside
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Scopoletin
selenium
Sesamolin
Shilajit
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spirulina
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strawberry
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Trigalloyl glucose
turmeric
Tyrosol
ubiquinol
Uncaria
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vegetable blend (proprietary)
Vestitol
vitamin C
vitamin E
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wheat germ
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Xanthone
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Yumberry
Zinc

Other health conditions supported by Ribose-l-cysteine

Cardiovascular Disease
Diabetes
Free Radical Damage
Inflammation
Liver Detoxification

Products containing Ribose-l-cysteine

We currently have no products on Vitabase that contain this ingredient.