Evidence supporting the use of: Allium (unspecified)
For the health condition: Fungal Infections

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Synopsis

Source of validity: Scientific
Rating (out of 5): 3

Allium species, particularly garlic (Allium sativum), have a long history of use in traditional medicine for combating infections, including fungal infections. This traditional use is supported by a substantial body of scientific research. Laboratory studies have demonstrated that compounds found in garlic, such as allicin, exhibit broad-spectrum antifungal activity. For example, allicin has been shown to inhibit the growth of Candida albicans and other pathogenic fungi in vitro. Other Allium species, such as onion (Allium cepa), also contain sulfur-containing compounds with demonstrated antifungal effects in laboratory settings.

However, while in vitro studies and some animal research support the antifungal potential of Allium extracts, clinical evidence in humans remains limited. A few small-scale clinical trials and case reports suggest possible benefits for topical application of garlic preparations in treating conditions like tinea corporis (ringworm) and oral candidiasis, but these studies are often of low quality or have methodological limitations. There is insufficient high-quality evidence from large randomized controlled trials to definitively recommend Allium as a primary antifungal treatment in humans. Thus, the evidence for its use can be considered moderate (3/5), with promising laboratory data but less robust clinical validation.

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