Evidence supporting the use of: Allyl isothiocyanate
For the health condition: Fungal Infections

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Synopsis

Source of validity: Scientific
Rating (out of 5): 2

Allyl isothiocyanate (AITC) is a naturally occurring compound found in mustard, horseradish, and wasabi, and is known for its pungent flavor and odor. Its potential antifungal properties have been investigated in several in vitro and some in vivo studies. Research demonstrates that AITC exhibits inhibitory activity against a variety of fungal pathogens, including Aspergillus, Penicillium, and Fusarium species, as well as yeasts such as Candida albicans. The proposed mechanism involves disruption of fungal cell membranes and interference with cellular metabolism. However, most of the supporting evidence comes from laboratory experiments using isolated fungal cultures or food preservation models, rather than from well-designed clinical trials in humans.

There is limited evidence regarding the efficacy and safety of AITC for treating fungal infections in humans. Its use has not been widely adopted in clinical practice, and there are no major clinical guidelines recommending AITC for fungal infections. While the compound is promising as a food preservative with antifungal effects, and while its mechanism is plausible, further research is necessary to establish its therapeutic potential in humans. Thus, the use of allyl isothiocyanate for treating fungal infections is scientifically plausible but not yet clinically validated.

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Products containing allyl isothiocyanate

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