Evidence supporting the use of: Alpha-terpineol
For the health condition: Fungal Infections

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Synopsis

Source of validity: Scientific
Rating (out of 5): 2

Alpha-terpineol is a naturally occurring monoterpene alcohol found in many essential oils, such as tea tree, pine, and eucalyptus oils. Scientific studies have demonstrated that alpha-terpineol possesses antifungal activity in vitro against several pathogenic fungi, including Candida albicans and dermatophytes. For instance, research published in peer-reviewed journals has shown that alpha-terpineol can disrupt fungal cell membranes, leading to cell death. The proposed mechanisms include increased membrane permeability and interference with ergosterol biosynthesis, which is crucial for fungal cell membrane integrity.

However, most of the evidence for alpha-terpineol’s antifungal effects comes from laboratory (in vitro) studies, not from clinical trials in humans. There is a lack of robust, high-quality clinical data demonstrating its efficacy and safety when used to treat or support fungal infections in humans. Furthermore, it is often a component of essential oils rather than used as an isolated compound in medical practice. Therefore, while there is scientific rationale and preliminary laboratory evidence supporting its antifungal potential, clinical validation is limited, leading to a moderate evidence rating.

In summary, alpha-terpineol shows promise as an antifungal agent based on scientific studies in the laboratory, but more clinical research is necessary before it can be confidently recommended for the treatment or support of fungal infections in humans.

More about alpha-terpineol
More about Fungal Infections

Other ingredients used for Fungal Infections

10-Undecenoic Acid
3-Phenyllactic Acid
Agarikon Mushroom
Ajoene
Ajuga
Alantolactone
Allicin
Allium tuberosum
Allyl isothiocyanate
Allyl sulfide
Aloe vera
alpha-pinene
alpha-terpineol
Ampelopsis
anamu
Ardisia
babchi
Baphicacanthus cusia
barberry
Barleria
basil
bee hive
bee propolis
benzyl isothiocyanate
beta-pinene
bisabolene
black nightshade
black walnut
borneol
Brazilian peppertree
Caesalpinia crista
cajuput
Calendula
camphor oil
caprylic acid
carvacrol
caryophyllene
Centipeda
chalcone
chamomile
Cinnamomum
cinnamon
citral
citronella
coconut oil
commiphora
copaiba oil
curry leaf
Dianthus
eucalyptus
eugenol
Euphorbia
gamma-terpinene
garlic
geranial
geraniol
geranium
Glechoma hederacea
glyceryl caprylate caprate
glyceryl monolaurate
Gnaphalium
goldenseal
green tea
Hedyotis
henna
Herb Robert
Houttuynia
Indian fagonia
jojoba oil
Kefir
Labdanum
Lactoperoxidase
Laggera pterodonta
Lantana camara
lauric acid
Lebbek
lemongrass
Leptospermum scoparium
lichen
linalool
Litsea
liverwort
lodhtree
Macaranga indica
Mahonia
mangostin
marigold
Marking Nut Tree
melaleuca alternifolia
Melia
Menthol oil
Monolaurin
Morinda
Mountain Pepper
Mustard
Naphthoquinones
Neem tree
nut grass
Onosma bracteatum
oregano
oregon grape
oriental arborvitae
Oroxylum indicum
pau d'arco
Pentacyclic triterpenoids
phenolic compounds
phlorotannins
Plectranthus amboinicus
Plumbago zeylanica
Polygodial
polyphenols
Propolis
rosemary
rue
sage
Salvia
Sandalwood
Sapindus mukorossi
schizonepeta
Self-Heal
Soapberry
Sophora
Stereospermum
Storax
Sumac
Tea Tree Oil
Terpinen-4-ol
Terpinolene
Thaumatococcus daniellii
Thiosulfinate
Thuja
Thymol
Tulbaghia
turmeric
Undecylenic acid
Violet
Water Pepper
Winter Savory
Wrightia tinctoria
zanthoxylum
Zingiberene

Products containing alpha-terpineol

We currently have no products on Vitabase that contain this ingredient.