Evidence supporting the use of: Beta-pinene
For the health condition: Fungal Infections

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Synopsis

Source of validity: Scientific
Rating (out of 5): 2

Beta-pinene is a monoterpene commonly found in the essential oils of various plants, such as pine, rosemary, and basil. There is emerging scientific evidence supporting its antifungal activity, primarily from in vitro studies. Several laboratory investigations have demonstrated that beta-pinene can inhibit the growth of various pathogenic fungi, including Candida albicans, Aspergillus niger, and dermatophytes. The proposed mechanisms include disruption of the fungal cell membrane and interference with ergosterol biosynthesis, which is vital for fungal cell integrity.

For example, a 2012 study published in the Journal of Applied Microbiology showed that beta-pinene exhibited moderate antifungal effects against Candida species. Another study in Fitoterapia (2011) noted that beta-pinene isolated from essential oils contributed to overall antifungal activity against dermatophytes. However, these studies are predominantly preclinical, and there is a lack of robust clinical trials evaluating beta-pinene as a standalone treatment for fungal infections in humans.

In summary, while scientific evidence suggests potential antifungal properties of beta-pinene, the current level of evidence is limited to laboratory research. There is insufficient clinical data to fully validate its effectiveness or safety in treating fungal infections in humans. Thus, beta-pinene's use for this purpose is scientifically plausible but not yet clinically established.

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