Evidence supporting the use of: Bisabolol
For the health condition: Fungal Infections

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Synopsis

Source of validity: Scientific
Rating (out of 5): 2

Bisabolol is a naturally occurring monocyclic sesquiterpene alcohol, primarily found in chamomile (Matricaria recutita). It is well known for its anti-inflammatory, soothing, and skin-healing effects. Regarding fungal infections, bisabolol has demonstrated some in vitro antifungal activity against dermatophytes and yeasts such as Candida albicans and Trichophyton species. Several laboratory studies have reported that bisabolol can disrupt fungal cell membranes and inhibit the growth of certain pathogenic fungi. For example, research published in journals such as "Phytotherapy Research" and "Planta Medica" has shown that bisabolol, alone or in combination with other essential oil components, possesses moderate antifungal effects. However, most of these findings are limited to laboratory settings, and there is a lack of robust human clinical trials confirming its efficacy in treating fungal infections in real-world settings.

In summary, scientific evidence for bisabolol’s use against fungal infections exists, but it is preliminary and not yet strong enough to warrant widespread medical endorsement. Its inclusion in topical formulations for fungal skin conditions is usually as a supportive ingredient, leveraging its anti-inflammatory and skin-calming properties rather than as a primary antifungal agent. More clinical research is needed to determine its true therapeutic value in this context.

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