Evidence supporting the use of: Borate
For the health condition: Fungal Infections
Synopsis
Source of validity: Scientific
Rating (out of 5): 4
Borate compounds, most notably boric acid (a form of borate), have a well-established history in the treatment of certain fungal infections, especially vulvovaginal candidiasis (yeast infections). Scientific studies support their effectiveness, particularly in cases where infection is caused by non-albicans Candida species or is resistant to standard antifungal treatments. The antifungal activity of borates is attributed to their ability to disrupt fungal cell walls and alter intracellular pH, thereby inhibiting fungal growth and replication.
Randomized controlled trials and systematic reviews have demonstrated that intravaginal boric acid (usually 600 mg in a gelatin capsule for 14 days) is an effective and relatively safe alternative for recurrent or resistant yeast infections. It is generally recommended as a second-line or adjunctive therapy by medical guidelines, including those of the Centers for Disease Control and Prevention (CDC).
However, while most evidence centers on boric acid, the term "borate (unspecified)" could encompass a range of boron-containing compounds, not all of which have been widely studied for antifungal use. Safety considerations are important, as borate compounds can be toxic if ingested or used improperly. Overall, the scientific evidence for boric acid (a borate) as an antifungal agent is strong, especially for topical use in treating specific fungal infections.
Other ingredients used for Fungal Infections
ajoenealoe vera
alpha-pinene
barberry
basil
beta-pinene
bisabolol
black walnut
caprylic acid
chamomile
cinnamon
turmeric
goldenseal
green tea
lactoperoxidase
lauric acid
monolaurin
oregano
oregon grape
phenolic acids
rosemary
sage
schizonepeta
undecylenic acid
neem tree
nut grass
commiphora
caesalpinia crista
pau d'arco
lemongrass
morinda
oriental arborvitae
zanthoxylum
polyphenols
eucalyptus
camphor oil
menthol oil
melaleuca alternifolia
geranium
10-Undecenoic Acid
3-Phenyllactic Acid
Agarikon Mushroom
Alpha-terpineol
Ardisia
Allicin
Anamu
Ajuga
Ampelopsis
Allyl Sulfide
allyl isothiocyanate
Allium tuberosum
Alantolactone
Bee Propolis
Babchi
Baphicacanthus cusia
Barleria
Brazillian peppertree
Bisabolene
Bee hive
Borate
Black Nightshade
benzyl isothiocyanate
Borneol
Curry leaf
Caryophyllene
Calendula
Cinnamomum
coconut oil
Carvacrol
Cajuput
Citral
Centipeda
Chalcone
Copaiba Oil
Citronella
Dianthus
Euphorbia
Eugenol
Geraniol
Gnaphalium
Glyceryl monolaurate
gamma-terpinene
Garlic
Glyceryl caprylate caprate
Glechoma hederacea
Geranial
Hedyotis
Mustard
Sandalwood
Sumac
Other health conditions supported by Borate
Athlete's FootFungal Infections
Skin (infections)
Ulcerations (external)
Wounds and Sores