Evidence supporting the use of: Borate
For the health condition: Fungal Infections

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Synopsis

Source of validity: Scientific
Rating (out of 5): 4

Borate compounds, most notably boric acid (a form of borate), have a well-established history in the treatment of certain fungal infections, especially vulvovaginal candidiasis (yeast infections). Scientific studies support their effectiveness, particularly in cases where infection is caused by non-albicans Candida species or is resistant to standard antifungal treatments. The antifungal activity of borates is attributed to their ability to disrupt fungal cell walls and alter intracellular pH, thereby inhibiting fungal growth and replication.

Randomized controlled trials and systematic reviews have demonstrated that intravaginal boric acid (usually 600 mg in a gelatin capsule for 14 days) is an effective and relatively safe alternative for recurrent or resistant yeast infections. It is generally recommended as a second-line or adjunctive therapy by medical guidelines, including those of the Centers for Disease Control and Prevention (CDC).

However, while most evidence centers on boric acid, the term "borate (unspecified)" could encompass a range of boron-containing compounds, not all of which have been widely studied for antifungal use. Safety considerations are important, as borate compounds can be toxic if ingested or used improperly. Overall, the scientific evidence for boric acid (a borate) as an antifungal agent is strong, especially for topical use in treating specific fungal infections.

More about Borate
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Products containing Borate

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