Evidence supporting the use of: Carvacrol
For the health condition: Fungal Infections

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Synopsis

Source of validity: Scientific
Rating (out of 5): 3

Carvacrol is a monoterpenoid phenol found primarily in oregano oil, and it has attracted scientific interest for its antimicrobial properties, including antifungal effects. Several in vitro (laboratory) studies have demonstrated that carvacrol exhibits significant activity against a variety of pathogenic fungi, such as Candida albicans, Aspergillus species, and dermatophytes. The proposed mechanism involves disruption of the fungal cell membrane, leading to leakage of cellular contents and cell death. Some animal studies also suggest carvacrol can reduce fungal burden in infected tissues.

However, most of the evidence comes from laboratory and preclinical research rather than large-scale human clinical trials. There are a few small studies and case reports indicating potential benefit in topical applications for skin fungal infections, but these are not sufficient to firmly establish its effectiveness or safety in humans for systemic fungal infections. Carvacrol is commonly included in herbal antifungal formulations, and its use is partly traditional, but the primary justification now comes from laboratory-based scientific research. Major health authorities have not yet endorsed carvacrol as a standard antifungal treatment, and more robust clinical trials are needed to confirm its efficacy and safety profile in humans.

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Products containing Carvacrol

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