Evidence supporting the use of: Eugenol
For the health condition: Fungal Infections
Synopsis
Source of validity: Scientific
Rating (out of 5): 2
Eugenol, a major component of clove oil, has been studied for its antifungal properties in vitro and in animal models. Laboratory studies have demonstrated that eugenol can inhibit the growth of several fungal species, including Candida albicans and Aspergillus species. The proposed mechanisms of action include disruption of fungal cell membranes and interference with enzyme activity essential for fungal survival. Additionally, eugenol has shown synergistic effects when combined with conventional antifungal drugs, potentially enhancing their efficacy and helping to overcome resistance in some strains.
Despite promising laboratory results, clinical data supporting the use of eugenol for treating fungal infections in humans is limited. Most evidence comes from in vitro experiments or animal studies, which do not always translate into effective and safe treatments for humans. There are a few reports of topical preparations containing eugenol being used in dental practice to manage oral candidiasis, but these are not large-scale or rigorously controlled studies. At present, eugenol’s antifungal effects are recognized scientifically, but the evidence remains preliminary, and it is not widely adopted as a standard clinical treatment for fungal infections. More robust human clinical trials are needed to validate its efficacy and safety for this use.
Other ingredients used for Fungal Infections
10-Undecenoic Acid3-Phenyllactic Acid
Agarikon Mushroom
Ajoene
Ajuga
Alantolactone
Allicin
Allium tuberosum
Allyl isothiocyanate
Allyl sulfide
Aloe vera
alpha-pinene
alpha-terpineol
Ampelopsis
anamu
Ardisia
babchi
Baphicacanthus cusia
barberry
Barleria
basil
bee hive
bee propolis
benzyl isothiocyanate
beta-pinene
bisabolene
black nightshade
black walnut
borneol
Brazilian peppertree
Caesalpinia crista
cajuput
Calendula
camphor oil
caprylic acid
carvacrol
caryophyllene
Centipeda
chalcone
chamomile
Cinnamomum
cinnamon
citral
citronella
coconut oil
commiphora
copaiba oil
curry leaf
Dianthus
eucalyptus
eugenol
Euphorbia
gamma-terpinene
garlic
geranial
geraniol
geranium
Glechoma hederacea
glyceryl caprylate caprate
glyceryl monolaurate
Gnaphalium
goldenseal
green tea
Hedyotis
henna
Herb Robert
Houttuynia
Indian fagonia
jojoba oil
Kefir
Labdanum
Lactoperoxidase
Laggera pterodonta
Lantana camara
lauric acid
Lebbek
lemongrass
Leptospermum scoparium
lichen
linalool
Litsea
liverwort
lodhtree
Macaranga indica
Mahonia
mangostin
marigold
Marking Nut Tree
melaleuca alternifolia
Melia
Menthol oil
Monolaurin
Morinda
Mountain Pepper
Mustard
Naphthoquinones
Neem tree
nut grass
Onosma bracteatum
oregano
oregon grape
oriental arborvitae
Oroxylum indicum
pau d'arco
Pentacyclic triterpenoids
phenolic compounds
phlorotannins
Plectranthus amboinicus
Plumbago zeylanica
Polygodial
polyphenols
Propolis
rosemary
rue
sage
Salvia
Sandalwood
Sapindus mukorossi
schizonepeta
Self-Heal
Soapberry
Sophora
Stereospermum
Storax
Sumac
Tea Tree Oil
Terpinen-4-ol
Terpinolene
Thaumatococcus daniellii
Thiosulfinate
Thuja
Thymol
Tulbaghia
turmeric
Undecylenic acid
Violet
Water Pepper
Winter Savory
Wrightia tinctoria
zanthoxylum
Zingiberene
Other health conditions supported by eugenol
Abdominal PainAcne
Antibiotics (alternatives to)
Anxiety
Arthritis
Bites and Stings
Boils
Bronchitis
Burns and Scalds
Canker Sores
Congestion (sinus)
Cuts
Ear Infection or Earache
Fungal Infections
Gingivitis
Hair (loss or thinning)
Headache (general)
Herpes
Infection
Infection (bacterial)
Inflammation
Itching
Oral Surgery
Pain (general remedies for)
