Evidence supporting the use of: Gamma-terpinene
For the health condition: Fungal Infections

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Synopsis

Source of validity: Scientific
Rating (out of 5): 2

Gamma-terpinene is a monoterpene commonly found in the essential oils of plants such as Tea tree (Melaleuca alternifolia), Cumin (Cuminum cyminum), and Coriander (Coriandrum sativum). Its use in the support or treatment of fungal infections is primarily grounded in laboratory-based scientific studies. Several in vitro studies have demonstrated that gamma-terpinene possesses antifungal activity against various fungal species, including Candida albicans and Aspergillus niger. For example, essential oils containing gamma-terpinene have been shown to disrupt fungal cell membranes and inhibit fungal growth.

However, it is important to note that the evidence is mainly preclinical. Most studies have been conducted using isolated fungal cultures or animal models, and there is a lack of robust clinical trials in humans specifically evaluating gamma-terpinene as a standalone antifungal agent. Additionally, in essential oils, gamma-terpinene is typically present alongside other active compounds (such as terpinen-4-ol in tea tree oil) that also contribute to antifungal effects, making it difficult to attribute the activity solely to gamma-terpinene.

In summary, there is scientific basis for the antifungal potential of gamma-terpinene, but the evidence is limited and primarily laboratory-based, resulting in a moderate evidence rating of 2 out of 5 for its use in supporting or treating fungal infections.

More about gamma-terpinene
More about Fungal Infections

Products containing gamma-terpinene

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