Evidence supporting the use of: Hedyotis (unspecified)
For the health condition: Fungal Infections

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Synopsis

Source of validity: Traditional
Rating (out of 5): 1

Hedyotis, also known as Oldenlandia, is a genus of plants used in traditional medicine systems, particularly in Asia. The most commonly referenced species is Hedyotis diffusa, used in Traditional Chinese Medicine (TCM). In TCM, Hedyotis is primarily valued for its purported "heat-clearing" and detoxifying properties and is more frequently used for conditions such as infections, inflammation, and even cancers rather than specifically for fungal infections. There are some traditional records and folk uses where Hedyotis has been applied to various skin conditions, which could potentially include fungal infections, but these mentions are rare and not central to its historical use profile.

Scientifically, there is minimal direct evidence supporting the use of Hedyotis species specifically for treating fungal infections. Some in vitro studies have identified certain extracts of Hedyotis diffusa and related species to possess weak antifungal activity against common pathogens like Candida albicans, but these findings are limited, preliminary, and have not been substantiated in clinical trials. Therefore, its use for fungal infections is based primarily on tradition, with only limited anecdotal support and very low-quality scientific evidence. Stronger evidence exists for its anti-inflammatory and anticancer properties rather than antifungal effects.

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