Evidence supporting the use of: Isothiocyanate
For the health condition: Fungal Infections

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Synopsis

Source of validity: Scientific
Rating (out of 5): 2

Isothiocyanates are a class of phytochemicals found in cruciferous vegetables such as broccoli, mustard, and horseradish. There is some scientific evidence to suggest that various isothiocyanates, particularly allyl isothiocyanate (AITC), possess antifungal properties in laboratory settings. In vitro studies have demonstrated that isothiocyanates can inhibit the growth of several fungal species, including Candida albicans, Aspergillus niger, and Fusarium species. The mechanism is thought to involve disruption of fungal cell membranes and inhibition of critical enzymatic processes within the fungi.

However, the evidence is currently limited to laboratory and some animal studies, with very few clinical trials evaluating the effectiveness or safety of isothiocyanates for treating fungal infections in humans. While these findings are promising and suggest a potential therapeutic role, there is insufficient high-quality, clinical evidence to support isothiocyanates as a standard treatment for fungal infections in humans. Additionally, there is no significant tradition of their use for this purpose in herbal or ethnobotanical medicine; their application is primarily driven by recent scientific discoveries.

In summary, isothiocyanates exhibit antifungal activity in preclinical settings, but more research, particularly in human subjects, is needed to validate their clinical efficacy and safety for treating fungal infections.

More about Isothiocyanate
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Products containing Isothiocyanate

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