Evidence supporting the use of: Mangostin
For the health condition: Fungal Infections

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Synopsis

Source of validity: Scientific
Rating (out of 5): 2

Mangostin, particularly alpha-mangostin, is a xanthone compound derived from the mangosteen fruit (Garcinia mangostana). There is emerging scientific evidence suggesting that mangostin possesses antifungal properties, primarily demonstrated in in vitro studies. Several laboratory experiments have shown that alpha-mangostin can inhibit the growth of pathogenic fungi, such as Candida albicans and Aspergillus niger, by disrupting fungal cell membranes and inhibiting biofilm formation (PubMed ID: 24689250; PubMed ID: 17020243). However, there is a significant gap between in vitro findings and clinical application. To date, there are no published human clinical trials evaluating the efficacy or safety of mangostin for treating fungal infections. The evidence is thus limited to laboratory research, and there is no established dosage, formulation, or regulatory approval for its use as an antifungal agent in humans. While traditional medicine systems in Southeast Asia have used mangosteen pericarp for various ailments, specific use for fungal infections is not well documented in ethnobotanical literature. In summary, mangostin’s antifungal potential is primarily supported by preclinical research. Its use for fungal infections cannot be recommended based on current clinical evidence, but scientific interest continues due to promising laboratory results.

More about mangostin
More about Fungal Infections

Other ingredients used for Fungal Infections

10-Undecenoic Acid
3-Phenyllactic Acid
Agarikon Mushroom
Ajoene
Ajuga
Alantolactone
Allicin
Allium tuberosum
Allyl isothiocyanate
Allyl sulfide
Aloe vera
alpha-pinene
alpha-terpineol
Ampelopsis
anamu
Ardisia
babchi
Baphicacanthus cusia
barberry
Barleria
basil
bee hive
bee propolis
benzyl isothiocyanate
beta-pinene
bisabolene
black nightshade
black walnut
borneol
Brazilian peppertree
Caesalpinia crista
cajuput
Calendula
camphor oil
caprylic acid
carvacrol
caryophyllene
Centipeda
chalcone
chamomile
Cinnamomum
cinnamon
citral
citronella
coconut oil
commiphora
copaiba oil
curry leaf
Dianthus
eucalyptus
eugenol
Euphorbia
gamma-terpinene
garlic
geranial
geraniol
geranium
Glechoma hederacea
glyceryl caprylate caprate
glyceryl monolaurate
Gnaphalium
goldenseal
green tea
Hedyotis
henna
Herb Robert
Houttuynia
Indian fagonia
jojoba oil
Kefir
Labdanum
Lactoperoxidase
Laggera pterodonta
Lantana camara
lauric acid
Lebbek
lemongrass
Leptospermum scoparium
lichen
linalool
Litsea
liverwort
lodhtree
Macaranga indica
Mahonia
mangostin
marigold
Marking Nut Tree
melaleuca alternifolia
Melia
Menthol oil
Monolaurin
Morinda
Mountain Pepper
Mustard
Naphthoquinones
Neem tree
nut grass
Onosma bracteatum
oregano
oregon grape
oriental arborvitae
Oroxylum indicum
pau d'arco
Pentacyclic triterpenoids
phenolic compounds
phlorotannins
Plectranthus amboinicus
Plumbago zeylanica
Polygodial
polyphenols
Propolis
rosemary
rue
sage
Salvia
Sandalwood
Sapindus mukorossi
schizonepeta
Self-Heal
Soapberry
Sophora
Stereospermum
Storax
Sumac
Tea Tree Oil
Terpinen-4-ol
Terpinolene
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Thiosulfinate
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Thymol
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Products containing mangostin

We currently have no products on Vitabase that contain this ingredient.