Evidence supporting the use of: Melia (unspecified)
For the health condition: Fungal Infections

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Synopsis

Source of validity: Traditional
Rating (out of 5): 2

The use of Melia, which commonly refers to Melia azedarach (chinaberry or Persian lilac), for treating fungal infections is primarily rooted in traditional medicine practices. In several cultures across Asia and Africa, extracts from Melia azedarach have been used in folk remedies for a range of ailments, including skin diseases and infections that may have a fungal origin. The traditional use often involves topical applications of leaf or bark extracts, or sometimes decoctions of the fruit, for skin conditions presumed to be fungal in nature.

Scientifically, there are a limited number of in vitro studies suggesting that Melia azedarach extracts possess some antifungal activity against certain dermatophytes and yeasts. For example, laboratory tests have indicated mild to moderate inhibition of fungal growth, likely due to the presence of limonoids and other secondary metabolites. However, these studies are preliminary, mostly conducted in vitro, and do not provide strong clinical evidence for efficacy in humans. No robust clinical trials or standardized protocols support Melia’s use as an antifungal agent in modern medicine.

In summary, while there is a traditional basis for using Melia azedarach for fungal infections and some limited laboratory data, the strength of scientific evidence is weak. Its current use for fungal infections is still primarily justified by traditional practices rather than rigorous scientific validation.

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