Evidence supporting the use of: Naphthoquinones
For the health condition: Fungal Infections

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Synopsis

Source of validity: Scientific
Rating (out of 5): 2

Naphthoquinones, particularly compounds like lapachol (from the Pau d'Arco tree) and plumbagin (from Plumbago species), have been studied for their antifungal properties. Several in vitro studies have demonstrated that naphthoquinones possess activity against a variety of pathogenic fungi, including Candida albicans and Aspergillus species. The mechanism of action is believed to involve the generation of reactive oxygen species, disruption of fungal cell membranes, and inhibition of essential fungal enzymes. However, despite promising laboratory results, there is limited clinical evidence supporting their efficacy and safety in treating human fungal infections. Most of the research remains at the preclinical or laboratory stage, and few, if any, well-conducted human trials have been published. Additionally, naphthoquinones can be cytotoxic to human cells, raising safety concerns for therapeutic use. While some traditional medicine systems have used plants containing naphthoquinones for antimicrobial purposes, the scientific community currently views their use for fungal infections as experimental, with more research needed to establish clinical benefits and safety profiles. Thus, the evidence supporting their use for fungal infections is limited and preliminary, meriting a score of 2 out of 5.

More about Naphthoquinones
More about Fungal Infections

Other ingredients used for Fungal Infections

10-Undecenoic Acid
3-Phenyllactic Acid
Agarikon Mushroom
Ajoene
Ajuga
Alantolactone
Allicin
Allium tuberosum
Allyl isothiocyanate
Allyl sulfide
Aloe vera
alpha-pinene
alpha-terpineol
Ampelopsis
anamu
Ardisia
babchi
Baphicacanthus cusia
barberry
Barleria
basil
bee hive
bee propolis
benzyl isothiocyanate
beta-pinene
bisabolene
black nightshade
black walnut
borneol
Brazilian peppertree
Caesalpinia crista
cajuput
Calendula
camphor oil
caprylic acid
carvacrol
caryophyllene
Centipeda
chalcone
chamomile
Cinnamomum
cinnamon
citral
citronella
coconut oil
commiphora
copaiba oil
curry leaf
Dianthus
eucalyptus
eugenol
Euphorbia
gamma-terpinene
garlic
geranial
geraniol
geranium
Glechoma hederacea
glyceryl caprylate caprate
glyceryl monolaurate
Gnaphalium
goldenseal
green tea
Hedyotis
henna
Herb Robert
Houttuynia
Indian fagonia
jojoba oil
Kefir
Labdanum
Lactoperoxidase
Laggera pterodonta
Lantana camara
lauric acid
Lebbek
lemongrass
Leptospermum scoparium
lichen
linalool
Litsea
liverwort
lodhtree
Macaranga indica
Mahonia
mangostin
marigold
Marking Nut Tree
melaleuca alternifolia
Melia
Menthol oil
Monolaurin
Morinda
Mountain Pepper
Mustard
Naphthoquinones
Neem tree
nut grass
Onosma bracteatum
oregano
oregon grape
oriental arborvitae
Oroxylum indicum
pau d'arco
Pentacyclic triterpenoids
phenolic compounds
phlorotannins
Plectranthus amboinicus
Plumbago zeylanica
Polygodial
polyphenols
Propolis
rosemary
rue
sage
Salvia
Sandalwood
Sapindus mukorossi
schizonepeta
Self-Heal
Soapberry
Sophora
Stereospermum
Storax
Sumac
Tea Tree Oil
Terpinen-4-ol
Terpinolene
Thaumatococcus daniellii
Thiosulfinate
Thuja
Thymol
Tulbaghia
turmeric
Undecylenic acid
Violet
Water Pepper
Winter Savory
Wrightia tinctoria
zanthoxylum
Zingiberene

Products containing Naphthoquinones

We currently have no products on Vitabase that contain this ingredient.