Evidence supporting the use of: Oroxylum indicum
For the health condition: Fungal Infections

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Synopsis

Source of validity: Scientific
Rating (out of 5): 2

Oroxylum indicum, commonly known as Indian trumpet tree or "Shyonaka," has a notable place in traditional medicine systems like Ayurveda. However, its use specifically for fungal infections is primarily supported by recent scientific investigations rather than strong traditional documentation. Several in vitro studies have demonstrated that extracts of Oroxylum indicum—particularly from the bark and seeds—exhibit antifungal activity against pathogens such as Candida albicans, Aspergillus niger, and Cryptococcus neoformans. These effects are attributed to various phytochemicals, including flavonoids (like baicalein and chrysin), tannins, and phenolic compounds present in the plant.

Despite these promising laboratory results, there is a lack of robust clinical evidence in humans to confirm its efficacy for treating fungal infections. The majority of existing studies are limited to cell culture or animal models, with outcomes that have not yet been translated into clinical practice. Moreover, traditional literature on Oroxylum indicum primarily highlights its use for respiratory disorders, digestive issues, and inflammatory conditions, rather than for fungal infections specifically.

Overall, while there is some scientific validation for the antifungal properties of Oroxylum indicum in preclinical settings, the evidence is preliminary and insufficient for strong clinical recommendations. Thus, the current body of evidence merits a rating of 2 out of 5.

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