Evidence supporting the use of: Phlorotannins
For the health condition: Fungal Infections

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Synopsis

Source of validity: Scientific
Rating (out of 5): 2

Phlorotannins are a class of polyphenolic compounds found exclusively in brown seaweeds. There is emerging scientific evidence supporting their antifungal properties, primarily from in vitro (laboratory) studies. Research has demonstrated that phlorotannins extracted from various species of brown algae can inhibit the growth of pathogenic fungi, such as Candida albicans and Aspergillus species. The proposed mechanisms include disruption of fungal cell membranes, inhibition of key fungal enzymes, and interference with biofilm formation, which is critical for the persistence of fungal infections.

However, most of the evidence comes from preclinical studies using isolated fungal strains and cell cultures, rather than human clinical trials. There are currently no well-designed human studies or clinical trials demonstrating the efficacy of phlorotannins in treating or preventing fungal infections. While the in vitro findings are promising and suggest that phlorotannins have potential as antifungal agents, much more research is needed to establish their safety, optimal dosing, and effectiveness in humans. Therefore, while there is some scientific basis for the use of phlorotannins in supporting the management of fungal infections, the level of evidence is still preliminary and does not yet justify widespread clinical use.

More about Phlorotannins
More about Fungal Infections

Products containing Phlorotannins

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