Evidence supporting the use of: Potassium caprylate
For the health condition: Fungal Infections

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Synopsis

Source of validity: Scientific
Rating (out of 5): 2

Potassium Caprylate and Fungal Infections: Evidence Overview

Potassium caprylate is the potassium salt of caprylic acid (octanoic acid), a medium-chain fatty acid found naturally in coconut oil and palm kernel oil. Its use in managing fungal infections—particularly Candida species—originates from the antifungal properties of caprylic acid observed in laboratory studies. In vitro, caprylic acid has demonstrated the ability to disrupt the cell membranes of fungi, leading to cell death. This mechanism is believed to underlie the rationale for using its salts, like potassium caprylate, as dietary supplements or adjunct therapies in cases of intestinal candidiasis and other minor fungal overgrowths.

Despite these promising laboratory findings, clinical evidence in humans is limited. No high-quality, large-scale randomized controlled trials have definitively established the efficacy of potassium caprylate or caprylic acid in treating systemic or even localized fungal infections. Most available data stem from small, non-randomized studies or anecdotal reports, often in conjunction with other antifungal interventions. Therefore, while there is a scientific basis for its antifungal action, the clinical relevance and effectiveness of potassium caprylate remain insufficiently validated. Regulatory agencies do not recognize it as a standard antifungal treatment.

In summary, potassium caprylate’s use for fungal infections is supported by basic scientific research but lacks robust clinical validation. It should not be considered a substitute for clinically proven antifungal medications.

More about Potassium caprylate
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Other health conditions supported by Potassium caprylate

Athlete's Foot
Fungal Infections
Thrush

Products containing Potassium caprylate

We currently have no products on Vitabase that contain this ingredient.