Relationship: GABA and l-taurine

Evidence supporting the use of: L-taurine
For the body system: GABA

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Synopsis

Source of validity: Scientific
Rating (out of 5): 3

L-taurine is an amino sulfonic acid found abundantly in the brain and several body tissues. Its use to support the GABAergic system is primarily based on scientific evidence rather than traditional use. Taurine is known to modulate inhibitory neurotransmission in the central nervous system. Several animal studies have shown that taurine can activate GABA_A and glycine receptors, producing inhibitory effects similar to GABA itself. Additionally, taurine may increase GABA levels in the brain by influencing GABA synthesis and release, as well as inhibiting GABA transaminase, the enzyme that breaks down GABA.

Some research in rodent models has demonstrated that taurine supplementation can produce anxiolytic (anxiety-reducing) and anticonvulsant effects, consistent with enhanced GABAergic activity. However, direct clinical evidence in humans is limited; most human studies have focused on taurine's cardiovascular or metabolic effects, not specifically its GABAergic effects. Nonetheless, taurine's role as a neuromodulator and its ability to interact with GABA receptors provide a plausible scientific rationale for its use in supporting the GABA system.

Overall, while the mechanistic and preclinical evidence is reasonably strong, human clinical evidence is sparse, which limits the overall rating of scientific support.

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Other body systems supported by l-taurine

Blood
Brain
Circulatory System
Eyes
GABA
Heart
Liver
Mitochondria
Muscles
Nerves
Parasympathetic Nervous System
Specific Neurotransmitters
Sympathetic Nervous System

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Evidence supporting the use of: L-taurine
For the body system: GABA

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Other ingredients that support GABA

Health Concerns

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Evidence supporting the use of: L-taurineFor the body system: GABA

Table of Contents

Synopsis

Other ingredients that support GABA

Other body systems supported by l-taurine

Products containing l-taurine

Evidence supporting the use of: L-taurine
For the body system: GABA