Evidence supporting the use of: Celandine
For the body system: Gall Bladder

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Synopsis

Source of validity: Traditional
Rating (out of 5): 2

Celandine (Chelidonium majus) has a long history of traditional use for supporting the gall bladder and liver. In European folk medicine, celandine has been used as a remedy for biliary disorders, gallstones, and liver complaints. The plant's bitter compounds, including isoquinoline alkaloids such as chelidonine and berberine, are believed to stimulate bile flow and support digestion, which is thought to benefit the gall bladder system. Historical texts and traditional herbalists have often recommended celandine as a "cholagogue" (an agent that promotes the discharge of bile) and for relief of symptoms like jaundice or biliary colic.

However, scientific validation for these uses is limited. Some animal and in vitro studies suggest that celandine extracts may have choleretic (bile-stimulating) effects, but robust human clinical trials are lacking. Additionally, there are safety concerns: case reports have linked celandine to hepatotoxicity (liver toxicity), leading to regulatory warnings in some countries. Thus, while celandine's use for gall bladder support is rooted in tradition, the strength of scientific evidence is modest, and caution is warranted due to potential adverse effects.

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