Evidence supporting the use of: Glycochenodeoxycholic acid
For the body system: Gall Bladder
Synopsis
Source of validity: Scientific
Rating (out of 5): 4
Glycochenodeoxycholic acid is a primary bile acid naturally produced in the liver and is one of the main constituents of bile, which is essential for the digestion and absorption of fats. Scientifically, its role in supporting gall bladder function—specifically, the emulsification and solubilization of dietary fats—is well established. Glycochenodeoxycholic acid is involved in the formation of bile salts, which are stored in the gall bladder and released into the small intestine during digestion.
In clinical settings, bile acids (including glycochenodeoxycholic acid and others) have been studied for their ability to dissolve cholesterol gallstones and improve bile flow in certain liver and gall bladder diseases. While ursodeoxycholic acid is more commonly used therapeutically, glycochenodeoxycholic acid shares similar biochemical actions in the biliary system. Research indicates that supplementation with bile acids can help in conditions of bile acid deficiency or impaired bile flow, albeit with caution, as excessive levels may be hepatotoxic.
There is strong scientific evidence supporting the physiological necessity of glycochenodeoxycholic acid in gall bladder function, although its direct supplementation as a therapy is less common compared to other bile acids. Its use is based on a deep understanding of bile acid metabolism and their essential role in maintaining healthy digestive and gall bladder processes.
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Other body systems supported by Glycochenodeoxycholic acid
Digestive SystemGall Bladder
Gastrointestinal Tract
Hepatic System
Intestinal System
Liver