Evidence supporting the use of: Large-leaf gentian
For the body system: Gall Bladder

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Synopsis

Source of validity: Traditional
Rating (out of 5): 2

Large-leaf Gentian (Gentiana macrophylla) has been used traditionally in Chinese and other East Asian herbal medicine systems. In Traditional Chinese Medicine (TCM), it is known as "Qin Jiao" and is typically used to "clear heat," "dispel dampness," and support liver and gall bladder function. The herb is included in various classic TCM formulations aimed at alleviating symptoms like jaundice, swelling, and discomfort associated with gall bladder and liver disorders. Gentian species in general are recognized for their bitter principles (such as gentiopicroside), which are believed in traditional practice to stimulate bile secretion and digestive function, theoretically benefiting the gall bladder.

However, while there is some pharmacological research on Gentiana macrophylla suggesting anti-inflammatory and hepatoprotective effects in animal models, direct, rigorous scientific studies confirming its efficacy specifically for gall bladder health or disease in humans are lacking. Most modern usage to support the gall bladder relies on traditional beliefs and herbal texts rather than clinical trials or strong evidence. Thus, the justification for using Large-leaf Gentian to support the gall bladder is primarily traditional, with limited scientific validation at this time.

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