Evidence supporting the use of: Total Fat
For the body system: Gall Bladder

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Table of Contents

Synopsis

Source of validity: Scientific
Rating (out of 5): 4

Total fat, as a macronutrient, plays a scientifically validated role in supporting the gall bladder and its function. The gall bladder’s primary role is to store and concentrate bile produced by the liver, which is then released into the small intestine to aid in fat digestion. The presence of dietary fat in the small intestine is the main physiological trigger for gall bladder contraction and bile release. Scientific studies show that when fat is consumed, the hormone cholecystokinin (CCK) is released, prompting the gall bladder to contract and expel bile. This bile emulsifies dietary fats, enabling their absorption. Clinical and physiological textbooks, such as "Guyton and Hall Textbook of Medical Physiology," detail this process extensively.

Insufficient dietary fat can reduce gall bladder stimulation, potentially leading to bile stasis and increasing the risk of gallstones. Conversely, extremely high-fat diets or rapid weight loss can also provoke gall bladder issues, but moderate fat intake is considered necessary for normal gall bladder health. While the evidence does not support supplementing "total fat" as a discrete ingredient, it is clear that dietary fat is essential for gall bladder function. Thus, the role of dietary fat in gall bladder physiology is well-established in the scientific literature, earning a high evidence rating.

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