Evidence supporting the use of: Silybum
For the health condition: Gall Bladder (sluggish or removed)

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Synopsis

Source of validity: Traditional
Rating (out of 5): 2

Silybum marianum (milk thistle) has a long history of traditional use for supporting liver and gallbladder health. In various traditional medicine systems, particularly European herbalism, milk thistle has been used to address "sluggish" gallbladder, promote bile flow, and assist with digestive complaints thought to be related to gallbladder dysfunction. The seeds contain silymarin, a flavonolignan complex, which is believed to have hepatoprotective and choleretic (bile flow promoting) properties. However, most of the available modern scientific research on Silybum focuses on its effects on the liver, such as in hepatitis and cirrhosis, rather than directly on gallbladder function or diseases associated with gallbladder removal (cholecystectomy).

Some animal studies suggest silymarin may stimulate bile production and secretion, which could theoretically benefit individuals with reduced bile flow. However, robust clinical trials in humans specifically assessing gallbladder conditions or post-cholecystectomy support are lacking. Thus, while milk thistle is commonly included in herbal formulas for gallbladder support based on tradition, the scientific evidence is limited and indirect. The rating of 2 reflects some plausible mechanisms and traditional precedent, but insufficient direct clinical validation for this specific use.

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