Evidence supporting the use of: Milk thistle
For the health condition: Gall Stones
Synopsis
Source of validity: Traditional
Rating (out of 5): 1
Milk thistle (Silybum marianum) is primarily used in traditional herbal medicine to support liver and gallbladder health, including for conditions such as gallstones. Its use is rooted in centuries of folk medicine, particularly in Europe and the Mediterranean region. Traditional herbalists have believed that milk thistle’s active compounds, particularly silymarin, help to stimulate bile flow and support detoxification processes, which are thought to aid in preventing the formation of gallstones or supporting their passage.
However, scientific validation for milk thistle’s efficacy in treating or preventing gallstones is limited. Most clinical research on milk thistle focuses on its hepatoprotective (liver-protecting) effects, especially in cases of toxin-induced liver damage or chronic liver diseases like hepatitis and cirrhosis. There are very few clinical studies directly examining its effects on gallstone formation or treatment. Some laboratory and animal studies suggest that silymarin can enhance bile flow (choleretic activity), theoretically reducing the risk of gallstone formation, but these findings have not been robustly confirmed in human trials.
In summary, while milk thistle is traditionally used for gallbladder health and is sometimes recommended for gallstones in complementary medicine, there is insufficient scientific evidence to strongly support these uses. The overall quality and quantity of evidence for its efficacy in gallstone management are low, and its use for this purpose remains primarily traditional rather than evidence-based.
Other ingredients used for Gall Stones
artichokebarberry
radish
turmeric
dandelion
ginger
onion
knotweed
licorice root
Milk thistle
ox bile
phosphatidylcholine
vitamin C
Indian bael
bile salt
Trichosanthes
hydrangea
paw paw
apple cider vinegar
Aerva lanata
Alisma
Butea monosperma
bitter grass
borassus palm
Borassus aethiopum
bile acid
cynarin
chanca piedra
dehydrocholic acid
deoxycholic acid
Embelia
fiber
Glycodeoxycholic acid
Glycochenodeoxycholic acid
Hedyotis
Iris
Indian fagonia
madder
Prunus
Portulaca
Palo Azul
Sichuan Lovage
Southern Tsangshu
Silybum
Taurochenodeoxycholic acid
Taurodeoxycholic acid
Taraxacum
Other health conditions supported by Milk thistle
Abdominal PainAddictions (general remedies for)
Alcoholism
Cancer Treatment (reducing side effects)
Chemical Poisoning
Chemotherapy (reducing side effects)
Cirrhosis of the Liver
Environmental Pollution
Fat Metabolism (poor)
Fatty Liver Disease
Fibrosis
Gall Bladder (sluggish or removed)
Gall Stones
Hangover
Heavy Metal Poisoning
Hepatitis
Jaundice (adults)
Liver Detoxification
Poisoning (general)
Products containing Milk thistle
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PaleoCleanse Plus™Chocolate Detox Kit
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Plant Protein Cleanse Plus™ 570g
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SP Ultimate
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Super Milk Thistle X
Pure Encapsulations
Ultra Pure Pack
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UltraNutrient®
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UltraNutrient®
Vitabase
Vision Support
