Evidence supporting the use of: Acemannan
For the health condition: Gingivitis

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Synopsis

Source of validity: Scientific
Rating (out of 5): 3

Acemannan, a major polysaccharide extracted from Aloe vera, has been studied for its role in supporting the treatment of gingivitis. Several clinical and laboratory studies provide evidence for its effectiveness. Acemannan exhibits anti-inflammatory, immunomodulatory, and wound healing properties, which are pertinent to the pathophysiology of gingivitis—a condition characterized by inflammation of the gums due to plaque accumulation.

Clinical trials, including randomized controlled studies, have demonstrated that topical application of acemannan-containing gels can reduce gingival inflammation and bleeding. For example, a study published in the Journal of Clinical and Experimental Dentistry (2015) reported that patients using an acemannan hydrogel experienced statistically significant reductions in gingival index and bleeding scores compared to placebo. The proposed mechanisms include inhibition of pro-inflammatory cytokines, promotion of fibroblast proliferation, and enhanced tissue repair. Furthermore, acemannan's antimicrobial activity against oral pathogens may contribute to its therapeutic effects.

While the evidence base is not as extensive as that for standard therapies such as chlorhexidine, the available data suggest a moderate level of scientific validation for acemannan's adjunctive use in gingivitis management. Thus, the use of acemannan for gingivitis is justified based on a growing body of scientific research, meriting a mid-range evidence rating.

More about Acemannan
More about Gingivitis

Other ingredients used for Gingivitis

ajoene
aloe vera
anthocyanins
basil
myrobalan
betel
bifidobacterium bifidum
bifidobacterium longum
bio ecolian (proprietary)
bisabolol
black garlic
black pepper
black walnut
blackberry
Indian frankincense
bromelain
cat's claw
catechins
chamomile
cinnamon
citrus bioflavonoids
citrus sinensis (proprietary)
coating
coconut milk
Coptis chinensis
turmeric
epigallocatechin gallate (EGCG)
flavonols
ginger
goldenseal
gooseberry
gotu kola
grape
greek mountain tea
onion
green tea
lactobacillus casei
lactobacillus gasseri
lactobacillus lactis
lactiplantibacillus plantarum
lactobacillus reuteri
lactobacillus salivarius
lactoferrin
lactoperoxidase
lauric acid
lemon
licorice root
microbial enzymes (proprietary)
monolaurin
moringa
mustard seed
orange
oregano
oregon grape
parsley
peppermint oil
phellodendron amurense
quercetin
raspberry
rutin
sage
schizonepeta
slippery elm bark
specialized pro-resolving mediators (SPMs)
streptococcus thermophilus
triphala
vitamin C
vitamin E
xylitol
zinc
bentonite
typhonium
Indian bael
ferula assafoetida
commiphora
blackboard tree
caesalpinia crista
bee pollen
peony
myrrh
sweet flag
morinda
trichosanthes
zanthoxylum
polyphenols
trace minerals
fulvic acid
menthol oil
aster root
paw paw
white oak
melaleuca alternifolia
enzymes blend (proprietary)
cayenne pepper
geranium
Avens
Apple Cider Vinegar
Alpha-terpineol
Ardisia
acacia
Allicin
Anamu
Ajuga
Alpha Hydroxy Acids
American Liverleaf
Asam gelugor
anthocyanidins
Acemannan
Ananain
Allium tuberosum
Amor seco
Arani
Bee Propolis
Black Seed
Babchi
Baphicacanthus cusia
Broussonetia
Blepharis
Balsam
Boswellic Acid
Bayleaf
Butea monosperma
Barleria
Bitter Grass
Bee hive
Banyan
Bioflavonoids
Black Nightshade
Bombax
Borassus Palm
Borassus aethiopum
Bacteria
Blue-Green Alage
Bacillus
benzyl isothiocyanate
Borneol
Camellia sinensis
Caryophyllene
Calendula
Cinnamomum
Clerodendrum trichotomum
Chlorophyllin
coconut oil
Carvacrol
Cajuput
Centella asiatica
Centipeda
Cistus
Corktree
Costus
Carthamus
Copaiba Oil
Celosia
Dianthus
Dichrostachys glomerata
Ellagic Acid
Empresstree
Elephant's Head
Euphorbia
Eugenol
Flavonones
Garlic
Galangal
Mustard
Mallow
Metal Salt
Sumac
Zucchini

Products containing Acemannan

We currently have no products on Vitabase that contain this ingredient.