Evidence supporting the use of: Antioxidant (unspecified)
For the health condition: Gingivitis
Synopsis
Source of validity: Scientific
Rating (out of 5): 2
Antioxidants have been investigated for their potential role in the management of gingivitis, primarily due to the recognition that oxidative stress contributes to the pathogenesis of periodontal diseases, including gingivitis. Gingival inflammation is associated with increased production of reactive oxygen species (ROS) by immune cells, leading to tissue damage. Antioxidants, both dietary (such as vitamin C, vitamin E, and polyphenols) and topical (such as coenzyme Q10 or plant extracts), are thought to counteract ROS and reduce oxidative damage.
Several small-scale clinical studies and reviews suggest that antioxidant supplementation or topical application may modestly reduce gingival inflammation and bleeding when used alongside standard oral hygiene practices. For example, studies with vitamin C supplementation have shown improvement in gingival health, particularly in individuals with deficiencies. Topical antioxidants, like coenzyme Q10 gels, have also been studied with some positive effects on gingival indices.
However, the overall quality of evidence is moderate to low. Most studies are limited by small sample sizes, short duration, and heterogeneous methodologies. Systematic reviews, such as those published in the Journal of Clinical Periodontology and Frontiers in Physiology, generally conclude that while antioxidants may offer adjunctive benefits, more robust clinical trials are needed to confirm their efficacy and establish clear recommendations. Thus, there is scientific rationale and some supporting evidence, but it is not yet conclusive or strong.
Other ingredients used for Gingivitis
ajoenealoe vera
anthocyanins
basil
myrobalan
betel
bifidobacterium bifidum
bifidobacterium longum
bio ecolian (proprietary)
bisabolol
black garlic
black pepper
black walnut
blackberry
Indian frankincense
bromelain
cat's claw
catechins
chamomile
cinnamon
citrus bioflavonoids
citrus sinensis (proprietary)
coating
coconut milk
Coptis chinensis
turmeric
epigallocatechin gallate (EGCG)
flavonols
ginger
goldenseal
gooseberry
gotu kola
grape
greek mountain tea
onion
green tea
lactobacillus casei
lactobacillus gasseri
lactobacillus lactis
lactiplantibacillus plantarum
lactobacillus reuteri
lactobacillus salivarius
lactoferrin
lactoperoxidase
lauric acid
lemon
licorice root
microbial enzymes (proprietary)
monolaurin
moringa
mustard seed
orange
oregano
oregon grape
parsley
peppermint oil
phellodendron amurense
quercetin
raspberry
rutin
sage
schizonepeta
slippery elm bark
specialized pro-resolving mediators (SPMs)
streptococcus thermophilus
triphala
vitamin C
vitamin E
xylitol
zinc
bentonite
typhonium
Indian bael
ferula assafoetida
commiphora
blackboard tree
caesalpinia crista
bee pollen
peony
myrrh
sweet flag
morinda
trichosanthes
zanthoxylum
polyphenols
trace minerals
fulvic acid
menthol oil
aster root
paw paw
white oak
melaleuca alternifolia
enzymes blend (proprietary)
cayenne pepper
geranium
Avens
Apple Cider Vinegar
Alpha-terpineol
Ardisia
acacia
Allicin
Anamu
Ajuga
Alpha Hydroxy Acids
American Liverleaf
Asam gelugor
anthocyanidins
Acemannan
Ananain
Allium tuberosum
Amor seco
Arani
Bee Propolis
Black Seed
Babchi
Baphicacanthus cusia
Broussonetia
Blepharis
Balsam
Boswellic Acid
Bayleaf
Butea monosperma
Barleria
Bitter Grass
Bee hive
Banyan
Bioflavonoids
Black Nightshade
Bombax
Borassus Palm
Borassus aethiopum
Bacteria
Blue-Green Alage
Bacillus
benzyl isothiocyanate
Borneol
Camellia sinensis
Caryophyllene
Calendula
Cinnamomum
Clerodendrum trichotomum
Chlorophyllin
coconut oil
Carvacrol
Cajuput
Centella asiatica
Centipeda
Cistus
Corktree
Costus
Carthamus
Copaiba Oil
Celosia
Dianthus
Dichrostachys glomerata
Ellagic Acid
Empresstree
Elephant's Head
Euphorbia
Eugenol
Flavonones
Garlic
Galangal
Mustard
Mallow
Metal Salt
Sumac
Zucchini
Other health conditions supported by Antioxidant (unspecified)
Age SpotsAging (prevention)
Alzheimer's Disease
Arteriosclerosis
Arthritis
Asthma
Cancer (natural therapy for)
Cancer (prevention)
Cancer Treatment (reducing side effects)
Cardiovascular Disease
Cataracts
Chemotherapy (reducing side effects)
Cholesterol (high)
Chronic Obstructive Pulmonary Disorder
Circulation (poor)
Circulation (to the brain)
Depression
Diabetes
Diabetic Retinopathy
Fatty Liver Disease
Free Radical Damage
Gastritis
Gingivitis
Heart (weakness)
Hypertension
Inflammation
Inflammatory Bowel Disorders
Liver Detoxification
Lupus
Macular Degeneration
Memory and Brain Function
Metabolic Syndrome
Migraine
Parkinson's Disease
Radiation Sickness
Wrinkles