Evidence supporting the use of: Bifidobacterium bifidum
For the health condition: Gingivitis

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Synopsis

Source of validity: Scientific
Rating (out of 5): 2

Bifidobacterium bifidum is a probiotic bacterium that has been investigated for its potential benefits in oral health, including the management of gingivitis. Several scientific studies have explored the role of probiotics, including B. bifidum, in reducing inflammation and pathogenic bacterial load in the oral cavity. The proposed mechanisms include competitive inhibition of pathogenic bacteria (such as Porphyromonas gingivalis and Aggregatibacter actinomycetemcomitans), modulation of host immune response, and reinforcement of the oral mucosal barrier.

While the bulk of clinical research on probiotics for gingivitis focuses on strains like Lactobacillus reuteri and Lactobacillus salivarius, some pilot studies and randomized controlled trials have included B. bifidum—often as part of a probiotic blend. Evidence from these studies indicates modest improvements in clinical parameters such as gingival bleeding and plaque scores compared to placebo. However, the number of studies specifically isolating B. bifidum’s effects is limited, and most data come from small sample sizes or short-term interventions.

In summary, there is some scientific rationale and preliminary evidence supporting the use of B. bifidum for gingivitis, but the quality and quantity of evidence are currently limited. More robust, strain-specific clinical trials are necessary to confirm efficacy and optimal usage parameters for B. bifidum in gingivitis management.

More about bifidobacterium bifidum
More about Gingivitis

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ajoene
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anthocyanins
basil
myrobalan
betel
bifidobacterium bifidum
bifidobacterium longum
bio ecolian (proprietary)
bisabolol
black garlic
black pepper
black walnut
blackberry
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bromelain
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catechins
chamomile
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citrus bioflavonoids
citrus sinensis (proprietary)
coating
coconut milk
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turmeric
epigallocatechin gallate (EGCG)
flavonols
ginger
goldenseal
gooseberry
gotu kola
grape
greek mountain tea
onion
green tea
lactobacillus casei
lactobacillus gasseri
lactobacillus lactis
lactiplantibacillus plantarum
lactobacillus reuteri
lactobacillus salivarius
lactoferrin
lactoperoxidase
lauric acid
lemon
licorice root
microbial enzymes (proprietary)
monolaurin
moringa
mustard seed
orange
oregano
oregon grape
parsley
peppermint oil
phellodendron amurense
quercetin
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rutin
sage
schizonepeta
slippery elm bark
specialized pro-resolving mediators (SPMs)
streptococcus thermophilus
triphala
vitamin C
vitamin E
xylitol
zinc
bentonite
typhonium
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ferula assafoetida
commiphora
blackboard tree
caesalpinia crista
bee pollen
peony
myrrh
sweet flag
morinda
trichosanthes
zanthoxylum
polyphenols
trace minerals
fulvic acid
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geranium
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coconut oil
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