Synopsis

Source of validity: Scientific
Rating (out of 5): 2

Citrus bioflavonoids, a group of plant-derived compounds commonly found in citrus fruits, have been studied for their potential role in supporting oral health, including the management of gingivitis. The scientific evidence supporting their use is modest but notable. Bioflavonoids possess antioxidant and anti-inflammatory properties, which are relevant because gingivitis is characterized by inflammation of the gums due to bacterial plaque accumulation. Some laboratory and animal studies have shown that citrus bioflavonoids can inhibit the growth of oral pathogens and reduce inflammatory markers associated with gum disease. For example, hesperidin and naringin—two prominent citrus bioflavonoids—have been shown to modulate immune responses and reduce oxidative stress in gingival tissues.

A few small-scale clinical trials and pilot studies have evaluated the effect of bioflavonoid supplementation, sometimes combined with vitamin C, on gingivitis. Some reported reductions in gum bleeding and inflammation, but these studies often had small sample sizes and methodological limitations. While these results are promising, there is a lack of large, high-quality randomized controlled trials directly linking citrus bioflavonoid supplementation to significant clinical improvement in gingivitis. Therefore, the current scientific evidence is supportive but not conclusive, justifying a moderate rating. In summary, citrus bioflavonoids have a plausible biological rationale and preliminary clinical support for their role in supporting gum health and managing gingivitis, but more robust research is needed to fully validate their effectiveness.

More about citrus bioflavonoids
More about Gingivitis

Other ingredients used for Gingivitis

Other health conditions supported by citrus bioflavonoids

Products containing citrus bioflavonoids

Vitabase Active Woman's Multi
Douglas Laboratories Ascorbplex ® 1000 Buffered
Vitabase Bilberry Extract Plus
Metagenics Bone Builder Active
Douglas Laboratories C-Max ®
Vitabase Chewable Vitamin C
Metagenics Cortico-B5B6®
Metagenics Echinacea Synergy
Designs For Health Electrolyte Synergy™
Douglas Laboratories Hair, Skin and Nails Plus
Vitabase Hair, Skin & Nails Formula
Pure Encapsulations Hair/Skin/Nails Ultra
Metagenics ImmuCore
Metagenics Immune Defense Pack
Integrative Therapeutics K-PAX MitoNutrients
Vitabase Life's Essentials Plus
Douglas Laboratories Malic Acid + Magnesium
Metagenics Multigenics®
Metagenics Multigenics Intensive Care
Metagenics Multigenics Intensive Care without Iron
Metagenics Multigenics without Iron
Douglas Laboratories Natural C
Integrative Therapeutics Nutrivitamin No-Iron
Metagenics PhytoMulti™ Multivitamin
Metagenics PhytoMulti With Iron
Metagenics PhytoMulti Without Iron
Metagenics PhytoMultivitamin
Designs For Health Primal Multi™
Pure Encapsulations PurePals
Pure Encapsulations PurePals with Iron
Vitabase Quercetin Plus
Designs For Health Stellar C™
Metagenics Ultra Potent-C 1000
Metagenics Ultra Potent-C 500
Metagenics Ultra Potent-C Chewable
Metagenics Ultra Potent-C Powder
Douglas Laboratories Ultra Preventive ® Kids Grape Flavor
Douglas Laboratories Ultra Preventive ® Kids Orange Flavor
Thorne Vitamin C With Flavonoids
Integrative Therapeutics Vitamin C with Quercetin
Metagenics Wellness Essentials Active Daily Packs