Evidence supporting the use of: European Barberry
For the health condition: Gingivitis

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Synopsis

Source of validity: Scientific
Rating (out of 5): 3

European Barberry (Berberis vulgaris) and Gingivitis: Evidence Summary

European Barberry has a longstanding presence in traditional medicine, but its application for gum diseases, including gingivitis, has been increasingly assessed in scientific studies in recent years. The primary active constituent of Barberry is berberine, an isoquinoline alkaloid with known antimicrobial and anti-inflammatory properties.

Several in vitro and animal studies have demonstrated that berberine can inhibit the growth of periodontal pathogens such as Porphyromonas gingivalis and reduce inflammatory responses in gingival tissues. More recently, small-scale clinical trials have evaluated Barberry extracts in oral hygiene products. For example, randomized controlled trials comparing Barberry mouthwashes or gels to standard treatments like chlorhexidine have shown that Barberry preparations can significantly reduce gingival inflammation and plaque scores in patients with gingivitis, sometimes with fewer side effects than conventional agents.

Despite these promising results, the body of human research remains limited in both the number and scale of studies. Most available evidence comes from short-duration trials with modest sample sizes, often conducted in Iran or neighboring regions where Barberry is traditionally used. No major adverse effects have been reported in these trials.

In summary, there is moderate scientific evidence supporting the use of European Barberry in the management of gingivitis, primarily due to its antimicrobial and anti-inflammatory activities. However, larger and more robust clinical trials are needed before it can be considered a standard or primary therapy.

More about European Barberry
More about Gingivitis

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Products containing European Barberry

We currently have no products on Vitabase that contain this ingredient.