Evidence supporting the use of: Flavanol (mixture)
For the health condition: Gingivitis
Synopsis
Source of validity: Scientific
Rating (out of 5): 3
Flavanols, a subclass of flavonoids commonly found in cocoa, tea, apples, and certain berries, have been investigated for their potential role in supporting oral health, including the management of gingivitis. Gingivitis is characterized by inflammation of the gums, primarily as a response to bacterial plaque accumulation. The scientific rationale for using flavanol mixtures lies in their anti-inflammatory, antioxidant, and antimicrobial properties. Several in vitro and in vivo studies have demonstrated that flavanols can inhibit the growth of oral pathogens (such as Porphyromonas gingivalis), reduce inflammatory cytokine production, and decrease oxidative stress—all key factors in the pathogenesis of gingivitis.
A few small clinical studies and pilot trials have reported that flavanol-rich mouthwashes or dietary supplementation (e.g., with green tea catechins or cocoa extracts) may reduce gingival bleeding and plaque scores compared to placebo. However, these studies are typically short-term, involve limited sample sizes, and sometimes lack rigorous controls. Systematic reviews suggest a modest benefit, but emphasize the need for larger, high-quality randomized controlled trials to make definitive recommendations. Overall, the use of flavanol mixtures for gingivitis is supported by promising mechanistic and preliminary clinical evidence, but more robust data are required to fully validate their efficacy and establish optimal dosing and formulations.
Other ingredients used for Gingivitis
ajoenealoe vera
anthocyanins
basil
myrobalan
betel
bifidobacterium bifidum
bifidobacterium longum
bio ecolian (proprietary)
bisabolol
black garlic
black pepper
black walnut
blackberry
Indian frankincense
bromelain
cat's claw
catechins
chamomile
cinnamon
citrus bioflavonoids
citrus sinensis (proprietary)
coating
coconut milk
Coptis chinensis
turmeric
epigallocatechin gallate (EGCG)
flavonols
ginger
goldenseal
gooseberry
gotu kola
grape
greek mountain tea
onion
green tea
lactobacillus casei
lactobacillus gasseri
lactobacillus lactis
lactiplantibacillus plantarum
lactobacillus reuteri
lactobacillus salivarius
lactoferrin
lactoperoxidase
lauric acid
lemon
licorice root
microbial enzymes (proprietary)
monolaurin
moringa
mustard seed
orange
oregano
oregon grape
parsley
peppermint oil
phellodendron amurense
quercetin
raspberry
rutin
sage
schizonepeta
slippery elm bark
specialized pro-resolving mediators (SPMs)
streptococcus thermophilus
triphala
vitamin C
vitamin E
xylitol
zinc
bentonite
typhonium
Indian bael
ferula assafoetida
commiphora
blackboard tree
caesalpinia crista
bee pollen
peony
myrrh
sweet flag
morinda
trichosanthes
zanthoxylum
polyphenols
trace minerals
fulvic acid
menthol oil
aster root
paw paw
white oak
melaleuca alternifolia
enzymes blend (proprietary)
cayenne pepper
geranium
Avens
Apple Cider Vinegar
Alpha-terpineol
Ardisia
acacia
Allicin
Anamu
Ajuga
Alpha Hydroxy Acids
American Liverleaf
Asam gelugor
anthocyanidins
Acemannan
Ananain
Allium tuberosum
Amor seco
Arani
Bee Propolis
Black Seed
Babchi
Baphicacanthus cusia
Broussonetia
Blepharis
Balsam
Boswellic Acid
Bayleaf
Butea monosperma
Barleria
Bitter Grass
Bee hive
Banyan
Bioflavonoids
Black Nightshade
Bombax
Borassus Palm
Borassus aethiopum
Bacteria
Blue-Green Alage
Bacillus
benzyl isothiocyanate
Borneol
Camellia sinensis
Caryophyllene
Calendula
Cinnamomum
Clerodendrum trichotomum
Chlorophyllin
coconut oil
Carvacrol
Cajuput
Centella asiatica
Centipeda
Cistus
Corktree
Costus
Carthamus
Copaiba Oil
Celosia
Dianthus
Dichrostachys glomerata
Ellagic Acid
Empresstree
Elephant's Head
Euphorbia
Eugenol
Flavonones
Garlic
Galangal
Mustard
Mallow
Metal Salt
Sumac
Zucchini
Other health conditions supported by Flavanol (mixture)
Alzheimer's DiseaseArteriosclerosis
Cancer (prevention)
Cardiovascular Disease
Cholesterol (high)
Circulation (poor)
Colds (general)
Congestive Heart Failure
Diabetes
Diabetic Retinopathy
Digestion (poor)
Edema
Energy (lack of)
Fatigue
Fatty Liver Disease
Free Radical Damage
Gingivitis
Heart (weakness)
Hemorrhoids
Hypertension
Inflammation
Memory and Brain Function
Osteoporosis
Raynaud's Disease
Rheumatoid Arthritis
Skin Care (general)