Evidence supporting the use of: Fucoidan
For the health condition: Gingivitis
Synopsis
Source of validity: Scientific
Rating (out of 5): 2
Fucoidan is a sulfated polysaccharide primarily found in brown seaweed, and it has attracted attention for its potential bioactive properties, including anti-inflammatory and antimicrobial effects. Several preclinical studies have explored the impact of fucoidan on oral health, particularly its possible benefits in managing gingivitis. In vitro research has shown that fucoidan can inhibit the growth of oral pathogens, such as Porphyromonas gingivalis and Streptococcus mutans, which are implicated in gingivitis and other periodontal diseases. Additionally, animal models have demonstrated that fucoidan can reduce inflammatory markers and tissue destruction associated with periodontal disease.
However, evidence in humans is limited. A few early-stage clinical trials and pilot studies have evaluated mouthwashes or oral gels containing fucoidan, reporting some improvements in gum inflammation and bleeding compared to placebo. These studies suggest potential adjunctive benefits, likely due to fucoidan’s anti-inflammatory and antimicrobial activities. Nevertheless, these trials are small in scale, and methodological limitations (such as short duration and lack of blinding) mean that results should be interpreted with caution.
Fucoidan is not widely used in traditional medicine specifically for gingivitis, and its use in this context is primarily driven by recent scientific interest rather than established historical practices. While the preliminary data are promising, more robust, large-scale human trials are needed to establish the efficacy and safety of fucoidan for treating or supporting gingivitis.
Other ingredients used for Gingivitis
ajoenealoe vera
anthocyanins
basil
myrobalan
betel
bifidobacterium bifidum
bifidobacterium longum
bio ecolian (proprietary)
bisabolol
black garlic
black pepper
black walnut
blackberry
Indian frankincense
bromelain
cat's claw
catechins
chamomile
cinnamon
citrus bioflavonoids
citrus sinensis (proprietary)
coating
coconut milk
Coptis chinensis
turmeric
epigallocatechin gallate (EGCG)
flavonols
ginger
goldenseal
gooseberry
gotu kola
grape
greek mountain tea
onion
green tea
lactobacillus casei
lactobacillus gasseri
lactobacillus lactis
lactiplantibacillus plantarum
lactobacillus reuteri
lactobacillus salivarius
lactoferrin
lactoperoxidase
lauric acid
lemon
licorice root
microbial enzymes (proprietary)
monolaurin
moringa
mustard seed
orange
oregano
oregon grape
parsley
peppermint oil
phellodendron amurense
quercetin
raspberry
rutin
sage
schizonepeta
slippery elm bark
specialized pro-resolving mediators (SPMs)
streptococcus thermophilus
triphala
vitamin C
vitamin E
xylitol
zinc
bentonite
typhonium
Indian bael
ferula assafoetida
commiphora
blackboard tree
caesalpinia crista
bee pollen
peony
myrrh
sweet flag
morinda
trichosanthes
zanthoxylum
polyphenols
trace minerals
fulvic acid
menthol oil
aster root
paw paw
white oak
melaleuca alternifolia
enzymes blend (proprietary)
cayenne pepper
geranium
Avens
Apple Cider Vinegar
Alpha-terpineol
Ardisia
acacia
Allicin
Anamu
Ajuga
Alpha Hydroxy Acids
American Liverleaf
Asam gelugor
anthocyanidins
Acemannan
Ananain
Allium tuberosum
Amor seco
Arani
Bee Propolis
Black Seed
Babchi
Baphicacanthus cusia
Broussonetia
Blepharis
Balsam
Boswellic Acid
Bayleaf
Butea monosperma
Barleria
Bitter Grass
Bee hive
Banyan
Bioflavonoids
Black Nightshade
Bombax
Borassus Palm
Borassus aethiopum
Bacteria
Blue-Green Alage
Bacillus
benzyl isothiocyanate
Borneol
Camellia sinensis
Caryophyllene
Calendula
Cinnamomum
Clerodendrum trichotomum
Chlorophyllin
coconut oil
Carvacrol
Cajuput
Centella asiatica
Centipeda
Cistus
Corktree
Costus
Carthamus
Copaiba Oil
Celosia
Dianthus
Dichrostachys glomerata
Ellagic Acid
Empresstree
Elephant's Head
Euphorbia
Eugenol
Flavonones
Garlic
Galangal
Mustard
Mallow
Metal Salt
Sumac
Zucchini
Other health conditions supported by Fucoidan
ArthritisAutoimmune Disorders
Cancer (natural therapy for)
Cancer (prevention)
Cancer Treatment (reducing side effects)
Chemotherapy (reducing side effects)
Cholesterol (high)
Cirrhosis of the Liver
Colitis
Diabetes
Fatty Liver Disease
Fibrosis
Free Radical Damage
Gastritis
Gingivitis
Hepatitis
Infection
Infection (bacterial)
Infection (viral)
Inflammation
Inflammatory Bowel Disorders
Liver Detoxification