Synopsis

Source of validity: Traditional
Rating (out of 5): 2

Goldenseal (Hydrastis canadensis) has a long history of use in traditional herbal medicine, particularly among Native American tribes and later in Western herbalism. It has been employed for its antimicrobial and anti-inflammatory properties, largely attributed to its primary alkaloid component, berberine. For oral health, including conditions like gingivitis, goldenseal has been used as a mouthwash or rinse to reduce inflammation, soothe mucous membranes, and combat infection. Historical texts and herbal compendia from the 19th and early 20th centuries reference its application in treating oral sores, ulcers, and gum disease. However, modern scientific validation for its efficacy specifically in gingivitis is limited. A few laboratory studies have shown that berberine has antimicrobial effects against oral pathogens, and there are some small clinical studies suggesting herbal mouthwashes containing goldenseal may reduce plaque and gum inflammation. Still, these studies are generally low in number and quality, and goldenseal is rarely studied in isolation. The bulk of its use for gingivitis is thus rooted in tradition rather than robust clinical evidence. More rigorous, large-scale clinical trials are needed to determine its effectiveness and safety for this purpose.

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