Evidence supporting the use of: Mangostin
For the health condition: Gingivitis

Links: Go back one page, Tool main page, Ingredients list, Health conditions list, Body systems list

Synopsis

Source of validity: Scientific
Rating (out of 5): 2

Mangostin, a xanthone compound primarily derived from the pericarp of the mangosteen fruit (Garcinia mangostana), has shown some promise in supporting or treating gingivitis due to its reported anti-inflammatory and antimicrobial properties. Several in vitro and some limited clinical studies have investigated its effects on oral pathogens and gingival inflammation. For example, research published in the Journal of Clinical and Diagnostic Research (2017) and Journal of Oral Science (2011) reported that mouthwashes or gels containing mangosteen extract could reduce gingival bleeding and plaque scores compared to placebo, likely due to inhibition of bacterial growth and modulation of inflammatory pathways. However, these studies are generally small, short in duration, and sometimes lack rigorous controls or blinding.

Traditional use of mangostin or mangosteen for oral health is not well-documented; its application for gingivitis is a relatively recent development rooted in its phytochemical profile rather than ethnomedicinal history. As such, while preliminary scientific evidence suggests potential benefits, the overall quality and quantity of evidence remain limited, and more robust, larger-scale clinical trials are needed to confirm efficacy and long-term safety. Thus, the use of mangostin for gingivitis is supported by emerging scientific evidence, but cannot be considered a well-established or strongly validated therapy at this time.

More about Mangostin
More about Gingivitis

Other ingredients used for Gingivitis

ajoene
aloe vera
anthocyanins
basil
myrobalan
betel
bifidobacterium bifidum
bifidobacterium longum
bio ecolian (proprietary)
bisabolol
black garlic
black pepper
black walnut
blackberry
Indian frankincense
bromelain
cat's claw
catechins
chamomile
cinnamon
citrus bioflavonoids
citrus sinensis (proprietary)
coating
coconut milk
Coptis chinensis
turmeric
epigallocatechin gallate (EGCG)
flavonols
ginger
goldenseal
gooseberry
gotu kola
grape
greek mountain tea
onion
green tea
lactobacillus casei
lactobacillus gasseri
lactobacillus lactis
lactiplantibacillus plantarum
lactobacillus reuteri
lactobacillus salivarius
lactoferrin
lactoperoxidase
lauric acid
lemon
licorice root
microbial enzymes (proprietary)
monolaurin
moringa
mustard seed
orange
oregano
oregon grape
parsley
peppermint oil
phellodendron amurense
quercetin
raspberry
rutin
sage
schizonepeta
slippery elm bark
specialized pro-resolving mediators (SPMs)
streptococcus thermophilus
triphala
vitamin C
vitamin E
xylitol
zinc
bentonite
typhonium
Indian bael
ferula assafoetida
commiphora
blackboard tree
caesalpinia crista
bee pollen
peony
myrrh
sweet flag
morinda
trichosanthes
zanthoxylum
polyphenols
trace minerals
fulvic acid
menthol oil
aster root
paw paw
white oak
melaleuca alternifolia
enzymes blend (proprietary)
cayenne pepper
geranium
Avens
Apple Cider Vinegar
Alpha-terpineol
Ardisia
acacia
Allicin
Anamu
Ajuga
Alpha Hydroxy Acids
American Liverleaf
Asam gelugor
anthocyanidins
Acemannan
Ananain
Allium tuberosum
Amor seco
Arani
Bee Propolis
Black Seed
Babchi
Baphicacanthus cusia
Broussonetia
Blepharis
Balsam
Boswellic Acid
Bayleaf
Butea monosperma
Barleria
Bitter Grass
Bee hive
Banyan
Bioflavonoids
Black Nightshade
Bombax
Borassus Palm
Borassus aethiopum
Bacteria
Blue-Green Alage
Bacillus
benzyl isothiocyanate
Borneol
Camellia sinensis
Caryophyllene
Calendula
Cinnamomum
Clerodendrum trichotomum
Chlorophyllin
coconut oil
Carvacrol
Cajuput
Centella asiatica
Centipeda
Cistus
Corktree
Costus
Carthamus
Copaiba Oil
Celosia
Dianthus
Dichrostachys glomerata
Ellagic Acid
Empresstree
Evodia
Elephant's Head
Euphorbia
Eugenol
Flavonones
Garlic
Galangal
Mustard
Mallow
Metal Salt
Sumac
Zucchini

Products containing Mangostin

We currently have no products on Vitabase that contain this ingredient.