Evidence supporting the use of: Piper nigrum
For the health condition: Gingivitis
Synopsis
Source of validity: Traditional
Rating (out of 5): 2
Piper nigrum (black pepper) has a long history of use in traditional medicine systems, including Ayurveda and Traditional Chinese Medicine, for a variety of oral health issues, including gingivitis. In traditional practices, black pepper has been valued for its antimicrobial, anti-inflammatory, and antioxidant properties, and is sometimes included in herbal formulations or tooth powders intended to support gum health and reduce oral inflammation.
Scientifically, there is limited direct evidence evaluating the efficacy of Piper nigrum specifically for gingivitis. A few in vitro studies have demonstrated that extracts of black pepper possess antimicrobial activity against common oral pathogens, and piperine—the main bioactive alkaloid—has shown anti-inflammatory effects in various models. However, clinical trials or robust preclinical studies directly assessing the impact of black pepper or its constituents on gingivitis in humans are lacking.
In summary, the use of Piper nigrum for gingivitis is primarily justified by traditional practices and anecdotal reports, with limited low-level scientific support. Until more rigorous clinical studies are conducted, its use for this purpose should be regarded as traditional rather than evidence-based.
Other ingredients used for Gingivitis
ajoenealoe vera
anthocyanins
basil
myrobalan
betel
bifidobacterium bifidum
bifidobacterium longum
bio ecolian (proprietary)
bisabolol
black garlic
black pepper
black walnut
blackberry
Indian frankincense
bromelain
cat's claw
catechins
chamomile
cinnamon
citrus bioflavonoids
citrus sinensis (proprietary)
coating
coconut milk
Coptis chinensis
turmeric
epigallocatechin gallate (EGCG)
flavonols
ginger
goldenseal
gooseberry
gotu kola
grape
greek mountain tea
onion
green tea
lactobacillus casei
lactobacillus gasseri
lactobacillus lactis
lactiplantibacillus plantarum
lactobacillus reuteri
lactobacillus salivarius
lactoferrin
lactoperoxidase
lauric acid
lemon
licorice root
microbial enzymes (proprietary)
monolaurin
moringa
mustard seed
orange
oregano
oregon grape
parsley
peppermint oil
phellodendron amurense
quercetin
raspberry
rutin
sage
schizonepeta
slippery elm bark
specialized pro-resolving mediators (SPMs)
streptococcus thermophilus
triphala
vitamin C
vitamin E
xylitol
zinc
bentonite
typhonium
Indian bael
ferula assafoetida
commiphora
blackboard tree
caesalpinia crista
bee pollen
peony
myrrh
sweet flag
morinda
trichosanthes
zanthoxylum
polyphenols
trace minerals
fulvic acid
menthol oil
aster root
paw paw
white oak
melaleuca alternifolia
enzymes blend (proprietary)
cayenne pepper
geranium
Avens
Apple Cider Vinegar
Alpha-terpineol
Ardisia
acacia
Allicin
Anamu
Ajuga
Alpha Hydroxy Acids
American Liverleaf
Asam gelugor
anthocyanidins
Acemannan
Ananain
Allium tuberosum
Amor seco
Arani
Bee Propolis
Black Seed
Babchi
Baphicacanthus cusia
Broussonetia
Blepharis
Balsam
Boswellic Acid
Bayleaf
Butea monosperma
Barleria
Bitter Grass
Bee hive
Banyan
Bioflavonoids
Black Nightshade
Bombax
Borassus Palm
Borassus aethiopum
Bacteria
Blue-Green Alage
Bacillus
benzyl isothiocyanate
Borneol
Camellia sinensis
Caryophyllene
Calendula
Cinnamomum
Clerodendrum trichotomum
Chlorophyllin
coconut oil
Carvacrol
Cajuput
Centella asiatica
Centipeda
Cistus
Corktree
Costus
Carthamus
Copaiba Oil
Celosia
Dianthus
Dichrostachys glomerata
Ellagic Acid
Empresstree
Elephant's Head
Euphorbia
Eugenol
Flavonones
Garlic
Galangal
Mustard
Mallow
Metal Salt
Sumac
Zucchini
Other health conditions supported by Piper nigrum
Abdominal PainAcid Indigestion
Appetite (deficient)
Arthritis
Asthma
Athletic and Exercise Aids
Backache
Belching
Bronchitis
Cancer (natural therapy for)
Cancer (prevention)
Canker Sores
Colds (antiviral)
Colds (decongestant)
Colds (general)
Colds (prevention)
Colds (with fever)
Congestion (bronchial)
Congestion (lungs)
Congestion (sinus)
Constipation (children)
Cuts
Depression
Diabetes
Digestion (poor)
Fatigue
Fever
Gingivitis
Headache (general)
Headache (sinus)