Evidence supporting the use of: Procyanidol
For the health condition: Gingivitis
Synopsis
Source of validity: Scientific
Rating (out of 5): 2
Procyanidol, also known as procyanidins or proanthocyanidins, are a class of polyphenolic compounds found in plants such as grape seeds, pine bark, and cranberries. Their use in supporting or treating gingivitis is supported by a modest but growing body of scientific evidence. Several in vitro and animal studies have demonstrated that procyanidins exhibit significant antioxidant and anti-inflammatory properties, and may inhibit the growth of periodontal pathogens as well as reduce the production of pro-inflammatory mediators implicated in gingival inflammation.
Some small-scale human clinical trials have evaluated procyanidin-rich extracts (often from grape seed or pine bark) as adjuncts to standard oral hygiene in patients with gingivitis. These studies suggest that procyanidins may reduce gingival bleeding and plaque indices compared to placebo, likely due to their ability to modulate the inflammatory response and potentially limit bacterial adhesion to oral tissues. However, the quality and size of human trials remain limited, and systematic reviews have called for larger, more rigorous studies to confirm efficacy and determine optimal dosing and formulation.
In summary, there is preliminary scientific evidence supporting the use of procyanidins for gingivitis, but the current level of evidence is moderate at best. Their use is not solely traditional; it is based on emerging but not yet definitive clinical research.
Other ingredients used for Gingivitis
ajoenealoe vera
anthocyanins
basil
myrobalan
betel
bifidobacterium bifidum
bifidobacterium longum
bio ecolian (proprietary)
bisabolol
black garlic
black pepper
black walnut
blackberry
Indian frankincense
bromelain
cat's claw
catechins
chamomile
cinnamon
citrus bioflavonoids
citrus sinensis (proprietary)
coating
coconut milk
Coptis chinensis
turmeric
epigallocatechin gallate (EGCG)
flavonols
ginger
goldenseal
gooseberry
gotu kola
grape
greek mountain tea
onion
green tea
lactobacillus casei
lactobacillus gasseri
lactobacillus lactis
lactiplantibacillus plantarum
lactobacillus reuteri
lactobacillus salivarius
lactoferrin
lactoperoxidase
lauric acid
lemon
licorice root
microbial enzymes (proprietary)
monolaurin
moringa
mustard seed
orange
oregano
oregon grape
parsley
peppermint oil
phellodendron amurense
quercetin
raspberry
rutin
sage
schizonepeta
slippery elm bark
specialized pro-resolving mediators (SPMs)
streptococcus thermophilus
triphala
vitamin C
vitamin E
xylitol
zinc
bentonite
typhonium
Indian bael
ferula assafoetida
commiphora
blackboard tree
caesalpinia crista
bee pollen
peony
myrrh
sweet flag
morinda
trichosanthes
zanthoxylum
polyphenols
trace minerals
fulvic acid
menthol oil
aster root
paw paw
white oak
melaleuca alternifolia
enzymes blend (proprietary)
cayenne pepper
geranium
Avens
Apple Cider Vinegar
Alpha-terpineol
Ardisia
acacia
Allicin
Anamu
Ajuga
Alpha Hydroxy Acids
American Liverleaf
Asam gelugor
anthocyanidins
Acemannan
Ananain
Allium tuberosum
Amor seco
Arani
Bee Propolis
Black Seed
Babchi
Baphicacanthus cusia
Broussonetia
Blepharis
Balsam
Boswellic Acid
Bayleaf
Butea monosperma
Barleria
Bitter Grass
Bee hive
Banyan
Bioflavonoids
Black Nightshade
Bombax
Borassus Palm
Borassus aethiopum
Bacteria
Blue-Green Alage
Bacillus
benzyl isothiocyanate
Borneol
Camellia sinensis
Caryophyllene
Calendula
Cinnamomum
Clerodendrum trichotomum
Chlorophyllin
coconut oil
Carvacrol
Cajuput
Centella asiatica
Centipeda
Cistus
Corktree
Costus
Carthamus
Copaiba Oil
Celosia
Dianthus
Dichrostachys glomerata
Ellagic Acid
Empresstree
Elephant's Head
Euphorbia
Eugenol
Flavonones
Garlic
Galangal
Mustard
Mallow
Metal Salt
Sumac
Zucchini
Other health conditions supported by Procyanidol
Cardiovascular DiseaseCirculation (poor)
Diabetic Retinopathy
Edema
Free Radical Damage
Gingivitis
Inflammation
Skin Care (general)
Varicose Veins
Wrinkles