Evidence supporting the use of: Calotropis gigantea
For the health condition: Glands (swollen lymph)

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Synopsis

Source of validity: Traditional
Rating (out of 5): 2

Calotropis gigantea, commonly known as giant milkweed, has a longstanding presence in traditional medicine systems across South Asia, including Ayurveda, Unani, and folk medicine. It has been used topically and sometimes internally for a variety of ailments, including the treatment of swollen glands (which may refer to enlarged lymph nodes). Traditionally, the latex, leaves, or root bark of Calotropis gigantea are applied to the skin over swollen lymph nodes, believed to reduce swelling and inflammation. Descriptions of this use can be found in classic Ayurvedic texts such as the Charaka Samhita and Sushruta Samhita, as well as in ethnobotanical surveys from India and Southeast Asia.

However, scientific validation for this use is limited. While some studies have explored the anti-inflammatory and immunomodulatory properties of extracts from Calotropis gigantea, these investigations are mostly preclinical (in vitro or animal studies) and do not specifically address lymphadenopathy or the clinical treatment of swollen lymph nodes. No robust human clinical trials have confirmed its efficacy for this particular condition. Thus, while the traditional use of Calotropis gigantea for swollen glands is well-documented, current scientific evidence supporting this specific application is weak.

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Products containing Calotropis gigantea

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