Evidence supporting the use of: Centipeda minima
For the health condition: Glands (swollen lymph)

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Synopsis

Source of validity: Traditional
Rating (out of 5): 2

Centipeda minima, commonly known as sneezeweed, is primarily used in traditional medicine systems, especially in Traditional Chinese Medicine (TCM). In TCM, it is known as "E Bu Shi Cao" and has been used for centuries to treat a variety of conditions including respiratory ailments, nasal polyps, and swelling. The herb is traditionally believed to have properties that help reduce swelling and detoxify, which includes applications for swollen glands (often interpreted as swollen lymph nodes or lymphadenopathy). Historical texts and modern-day herbal guides frequently list Centipeda minima as a remedy for "phlegm nodules" and "scrofula," which are interpreted as swellings of lymph glands, particularly in the neck. However, scientific validation for this specific use is limited. While some pharmacological studies suggest Centipeda minima has anti-inflammatory and immune-modulating properties, direct clinical evidence supporting its efficacy in treating swollen lymph glands is lacking. Studies have mostly focused on its effects on allergic rhinitis, inflammation, and antimicrobial activity, often in vitro or in animal models. Thus, the use of Centipeda minima for swollen glands is sustained primarily by traditional use, with the strength of evidence rated as 2—reflecting a long history of use but a lack of robust clinical trials or modern scientific validation for this particular indication.

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