Phellodendron, also known as Huang Bai or Amur cork tree, is a traditional herb in Chinese medicine. Its bark has been historically used to address various inflammatory conditions and to "clear heat and dampness," concepts related to infection and swelling in traditional Chinese medical (TCM) theory. Specifically, Phellodendron is often included in herbal formulas intended for symptoms such as swollen glands, particularly in the context of lymphadenitis or throat infections. These uses are primarily based on TCM theories rather than modern biomedical understanding of the lymphatic system.

Scientific studies on Phellodendron have demonstrated anti-inflammatory, antimicrobial, and immunomodulatory effects, largely attributed to its bioactive compounds like berberine. However, direct clinical evidence supporting the efficacy of Phellodendron for treating swollen lymph glands (lymphadenopathy) in humans is lacking. Most research is preclinical (in vitro or animal studies) and focuses on general inflammation or specific pathogens, not on lymphatic swelling as a targeted outcome.

In summary, the use of Phellodendron for swollen glands is rooted in traditional practice, with some indirect scientific support for its anti-inflammatory effects, but there is insufficient direct clinical evidence to confidently recommend it for this purpose.