Synopsis

Source of validity: Scientific
Rating (out of 5): 2

7,8-Dihydroxyflavone (7,8-DHF) is a naturally occurring flavone that has gained attention for its ability to act as a small-molecule agonist of the TrkB receptor, which is the primary receptor for brain-derived neurotrophic factor (BDNF). Most research has focused on its neuroprotective and cognitive-enhancing properties due to its effects on neuronal survival, plasticity, and synaptic function. There is emerging, but limited, scientific interest in how 7,8-DHF may influence the glandular system, particularly the hypothalamic-pituitary-adrenal (HPA) axis, which integrates neurological and endocrine functions. Animal studies have reported that 7,8-DHF can modulate stress responses and may have indirect effects on adrenal gland function by influencing BDNF-TrkB signaling pathways. However, direct clinical evidence for supporting the overall glandular system in humans is lacking. There are no established traditional uses of 7,8-DHF for glandular health, and its application in this area is primarily based on mechanistic plausibility and preclinical (mostly animal) models. Therefore, while there is some scientific rationale for its potential effects on certain glandular functions, especially those tightly linked to neuroendocrine regulation, robust validation in humans is currently insufficient.

More about 7,8-Dihydroxyflavone
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Other ingredients that support Glandular System

7,8-Dihydroxyflavone
7-Keto-DHEA
Acemannan
adrenal cortex
Agnuside
Ajuga
Alfalfa
Algae
amino acids
Anamarrhena
Anemarrhena
anemarrhena asphodeloides
animal protein
antler
Aralia
Ascophyllum nodosum
ashitaba
Ashoka
ashwagandha
Asteraceae
astragalus
babassu
babchi
banyan
barbasco
Barleria
basil
bee pollen
bee products
beef
Beef liver
Berberis (unspecified)
Bidens pilosa
black cohosh
black seed
bladderwrack
blue cohosh
bovine
bovine kidney
bovine liver
bovine pancreas
bovine protein
Brassica
Brazil nut
broccoli
Brown Algae
Brussel sprouts
Bulbine natalensis
Bupleurum
bupleurum falcatum
bасора
Camellia sinensis
Canscora
capsicum
caterpillar mushroom
Ceanothus integerrimus
Celastrus
chaga mushroom
chaste tree
Chinese mountain ant
Chinese thoroughwax
Cinnamomum
cinnamon
Clary sage
cod liver oil
Codonopsis
coenzyme Q10 (CoQ10)
colostrum
Coptis chinensis
cordyceps
cowage seed
cruciferous
Cucurbita
Cyanotis vaga
dandelion
deer velvet
Dendrobium
devil\'s club
DHEA
DHEA (dehydroepiandrosterone)
Didymocarpus
diiodotyrosine
DIM (diindolylmethane)
dioscorea
diosgenin
dong quai
dong quai root
dwarf morning glory
eleuthero
elk antler
essential oil blend
eucommia
Eucommia ulmoides
Eurycoma Longifolia
eurycomanone
Fadogia agrestis
false unicorn root
fat liver oil
fatty acids
fennel
fenuside
figwort
flat-stem milk-vetch
fo-ti
forskohlii root
forskolin
fruit and vegetable blend (proprietary)
fungus
furostanols
gamma linolenic acid (GLA)
ganoderma
garlic bulb
gastrodia
ginseng
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golden eardrops
gooseberry
Greek mountain tea
green tea
greens blend (proprietary)
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lavender
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licorice root
lingzhi
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liquid liver fractions
lophatherum leaf
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maca
macaenes
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magnesium
maitake mushroom
mandrake
manganese
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onion
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pantothenic acid (vitamin B5)
parsley
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red clover
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rehmannia glutinosa
reishi mushroom
Rhaponticum
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riboflavin (vitamin B2)
rockweed
Rosabin
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rose oil
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royal jelly
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saw palmetto
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scrophularia root
seaweed
selenium
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sesame
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soybean
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suma
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thyroid substance
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tribulus
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Watercress
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wheat grass
whole adrenal glandular
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Withanolides
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Other body systems supported by 7,8-Dihydroxyflavone

Brain
Glandular System
Hypothalamus
Nerves
Parasympathetic Nervous System
Sympathetic Nervous System

Products containing 7,8-Dihydroxyflavone

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