Evidence supporting the use of: Agnuside
For the body system: Glandular System

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Synopsis

Source of validity: Traditional
Rating (out of 5): 3

Agnuside is a primary active constituent found in the fruit of Vitex agnus-castus (chaste tree). Traditionally, this plant has been used for centuries in European herbal medicine, particularly to support hormone balance and reproductive health in women. Its use is mainly associated with the regulation of menstrual cycles, relief from premenstrual syndrome (PMS), and management of certain symptoms related to menopause. The rationale for its effect on the glandular (endocrine) system is based on historical observations that suggest Vitex agnus-castus can influence pituitary gland function, especially the secretion of prolactin, thereby indirectly affecting other hormones. However, most of the supporting evidence comes from the whole plant extract rather than isolated agnuside. While some preliminary scientific studies have shown that Vitex extracts may modulate hormone levels, the direct role of agnuside itself in supporting the glandular system is not well established in clinical research. Nonetheless, due to the plant’s long-standing traditional use for hormonal and glandular imbalances, the use of agnuside-containing preparations is considered to be justified primarily by tradition, with moderate but not robust evidence.

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Other ingredients that support Glandular System

7,8-Dihydroxyflavone
7-Keto-DHEA
Acemannan
adrenal cortex
Agnuside
Ajuga
Alfalfa
Algae
amino acids
Anamarrhena
Anemarrhena
anemarrhena asphodeloides
animal protein
antler
Aralia
Ascophyllum nodosum
ashitaba
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ashwagandha
Asteraceae
astragalus
babassu
babchi
banyan
barbasco
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basil
bee pollen
bee products
beef
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Bidens pilosa
black cohosh
black seed
bladderwrack
blue cohosh
bovine
bovine kidney
bovine liver
bovine pancreas
bovine protein
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Brazil nut
broccoli
Brown Algae
Brussel sprouts
Bulbine natalensis
Bupleurum
bupleurum falcatum
bасора
Camellia sinensis
Canscora
capsicum
caterpillar mushroom
Ceanothus integerrimus
Celastrus
chaga mushroom
chaste tree
Chinese mountain ant
Chinese thoroughwax
Cinnamomum
cinnamon
Clary sage
cod liver oil
Codonopsis
coenzyme Q10 (CoQ10)
colostrum
Coptis chinensis
cordyceps
cowage seed
cruciferous
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dandelion
deer velvet
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dioscorea
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eucommia
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Eurycoma Longifolia
eurycomanone
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false unicorn root
fat liver oil
fatty acids
fennel
fenuside
figwort
flat-stem milk-vetch
fo-ti
forskohlii root
forskolin
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fungus
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ganoderma
garlic bulb
gastrodia
ginseng
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Glycyrrhizin
gokhru
golden eardrops
gooseberry
Greek mountain tea
green tea
greens blend (proprietary)
guayusa
Gugglesterone
guggul
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heal-all
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Indian nightshade
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iron
isothiocyanates
jasmine
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ketosterones
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macaenes
macamides
magnesium
maitake mushroom
mandrake
manganese
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noni
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onion
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phytocannabinoids
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pregnenolone
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protein
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vitamin A
vitamin B
vitamin B6
vitamin C
vitamin D
vitamin D3
vitamin E
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Vitexicarpin
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whole adrenal glandular
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Products containing Agnuside

We currently have no products on Vitabase that contain this ingredient.